Ruffert K, Wätzig V
Z Gesamte Inn Med. 1977 Mar 1;32(5):123-5.
22 chloramphenicol allergics, 10 penicillin allergics and 6 patients with a chromate eczema as well as altogether 34 non-allergic control persons with healthy skin were examined according to the skin chamber method. After addition of the adequate antigen (chloramphenicol, penicillin, ammonium bichromate) into one of the two simultaneously applied skin chambers in sensitized persons an inhibition of the leucocyte migration in the antigen chamber develops. The polymorphonuclear neutrophilic granulocytes mobilised into the inflammation field were regarded as indicator cells. 5 chloramphenicol allergics with eczematous skin abnormalities and all control persons were negative. The investigation method is simply to be performed and therefore it is particularly suitable for clinical routine work.
根据皮肤小室法对22名氯霉素过敏者、10名青霉素过敏者、6名患有铬酸盐湿疹的患者以及总共34名皮肤健康的非过敏对照者进行了检查。在致敏者同时应用的两个皮肤小室之一中加入适当的抗原（氯霉素、青霉素、重铬酸铵）后，抗原小室中的白细胞迁移受到抑制。迁移到炎症部位的多形核中性粒细胞被视为指示细胞。5名患有湿疹性皮肤异常的氯霉素过敏者和所有对照者均为阴性。该研究方法操作简单，因此特别适用于临床日常工作。
