Munyangi Jérôme, Lutgen Pierre
Faculté de Médecine,Université de Kolwezi, Democratic Republic of the Congo.
IFBV-BELHERB, Luxembourg.
Malariaworld J. 2020 Jun 1;11:3. eCollection 2020.
Arachidonic acid (AA or ARA) is an extremely important fatty acid involved in cell regulation. It is a polyunsaturated fatty acid (20:4n6) covalently bound in esterified form in membrane phospholipids of most body cells. Following irritation or injury, arachidonic acid is released and oxygenated by enzyme systems leading to the formation of an important group of inflammatory mediators, to the prostaglandins (PGE₂) by the cyclooxygenase enzyme. This paper describes the positive health effects of arachidonic acid on malaria and other tropical diseases.
花生四烯酸(AA或ARA)是一种参与细胞调节的极其重要的脂肪酸。它是一种多不饱和脂肪酸(20:4n6),以酯化形式共价结合在大多数体细胞的膜磷脂中。在受到刺激或损伤后,花生四烯酸会被酶系统释放并氧化,导致形成一组重要的炎症介质,通过环氧化酶形成前列腺素(PGE₂)。本文描述了花生四烯酸对疟疾和其他热带疾病的积极健康影响。