慢性侵蚀性龈炎（剥脱性龈炎）中牙间乳头活检的临床意义：148 例标本的回顾性双中心研究。

Clinical relevance of interdental papilla biopsy in chronic erosive gingivitis (desquamative gingivitis): retrospective bicentric study of 148 specimens.

机构信息

Department of Odontology, Oral Medicine and Oral Surgery, APHP Henri Mondor Hospital, Université de Paris, 1 Rue Gustave Eiffel, 94000, Créteil, France.

Department of Odontology, Oral Medicine and Oral Surgery, Bretonneau Hospital, Université de Paris France, Paris, France.

出版信息

BMC Oral Health. 2021 Sep 17;21(1):452. doi: 10.1186/s12903-021-01820-9.

DOI:10.1186/s12903-021-01820-9

PMID:34535102

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8447615/

Abstract

BACKGROUND

Chronic erosive gingivitis, also called desquamative gingivitis, defines a clinical picture that can be generated by several inflammatory and immune diseases. Pathology is therefore essential for the differential diagnosis. However, when the gingival lesion is initial, exclusive or predominant, selecting the biopsy site and protocol may be problematic due to tissue fragility. Especially since there are few studies on the subject, the aim of our study was to assess the protocol, diagnostic relevance and tolerance of an original protocol using interdental papilla biopsy.

METHODS

We conducted a retrospective bicentric study, from October 2011 to July 2019, including all patients with a chronic erosive gingivitis who had received, for diagnostic purposes, a interdental papilla biopsy.

RESULTS

The contribution levels for the two hospital departments were 94.7% and 97.1%, respectively. No postoperative complication was recorded in the short or long term.

CONCLUSION

The interdental papilla biopsy protocol is perfectly adapted to the anatomopathological examinations required to establish differential diagnosis of chronic erosive gingivitis. This surgical protocol is simple to perform, non iatrogenic with a very good tolerance and and accessible to all clinicians. It is highly efficient with an excellent contribution level. ClinicalTrials NCT04293718 (March 3, 2020). Health Data Hub N° F20201109083211 (November 9, 2020).

摘要

背景

慢性侵蚀性龈炎，又称剥脱性龈炎，是由多种炎症性和免疫性疾病引起的一种临床症状。因此，病理学对鉴别诊断至关重要。然而，当牙龈病变是初始的、排他的或主要的时，由于组织脆弱，选择活检部位和方案可能会有问题。特别是由于该主题的研究较少，我们的研究旨在评估使用牙间乳头活检的原始方案的诊断相关性和耐受性。

方法

我们进行了一项回顾性的双中心研究，从 2011 年 10 月至 2019 年 7 月，共纳入所有因诊断目的而接受牙间乳头活检的慢性侵蚀性龈炎患者。

结果

两个医院科室的参与度分别为 94.7%和 97.1%。在短期或长期内均未记录到术后并发症。

结论

牙间乳头活检方案非常适合建立慢性侵蚀性龈炎的鉴别诊断所需的解剖病理学检查。该手术方案易于操作，非医源性，具有极好的耐受性，且所有临床医生均可操作。它具有极高的效率，且参与度非常高。ClinicalTrials NCT04293718（2020 年 3 月 3 日）。Health Data Hub N° F20201109083211（2020 年 11 月 9 日）。