Myopia Research Lab, Prof. Brien Holden Eye Research Centre, L V Prasad Eye Institute, Hyderabad, India.
Bausch & Lomb Contact Lens Center, L V Prasad Eye Institute, Hyderabad, India.
Clin Exp Optom. 2022 Sep;105(7):761-770. doi: 10.1080/08164622.2021.1970480. Epub 2021 Sep 19.
The peripheral refraction profile in myopes with different corrective modalities varies significantly for both distance and near viewing and will have implications in managing myopia.
This study investigated how the magnitude of peripheral myopic defocus induced by Ortho-K varies with and without accommodation, and how this compares to single vision spectacles and soft-contact-lenses (SCL).
Relative peripheral refraction (RPR) of 18 young adults (spherical equivalent -1.00 D to -4.50 D) was determined along the horizontal meridian (±10°, ±20°, ±25°) during distance (3-metres) and near viewing (0.2-metres), and along vertical meridian (±10°, ±15°) for distance viewing alone. Measurements were obtained in an uncorrected state and with single vision spectacles, soft contact lens and Ortho-K. Changes in RPR and astigmatic components were compared between distance and near viewing with all different modalities.
A significant interaction (p = 0.02) between relative peripheral refraction and the target distance (distance and near viewing) was found among different refractive modalities. Single overnight Ortho-K lens wear alone led to relative peripheral myopia for both distance (mean RPR ± SE: -0.92 ± 0.21D and -1.04 ± 0.22D) and near viewing (-0.71 ± 0.17D and -0.76 ± 0.20D). Comparisons of relative peripheral refraction between different corrective modalities at each eccentricity indicated statistical significance of RPR at extreme locations along both temporal and nasal meridian (±20 and ±25°, p < 0.05). RPR with soft contact lenses and spectacles were similar for both distance and near viewing (p > 0.05).
Single overnight Ortho-K lens wear alone shifted the RPR in the myopic direction for both distance and near viewing in comparison with single vision spectacles and soft contact lenses. The Ortho-K lens designs that offer a large amount of mid-peripheral corneal steeping, in-turn leading to high relative peripheral myopia for both distance and near viewing and might offer beneficial effects on myopia control.
不同矫正方式的近视患者的周边屈光度在远距和近距观察时差异显著，这将对近视管理产生影响。
本研究旨在探讨角膜塑形术（Ortho-K）引起的周边远视离焦量的大小如何随调节而变化，以及与单焦点眼镜和软性隐形眼镜（SCL）相比如何变化。
18 名年轻成年人（等效球镜度为-1.00 D 至-4.50 D）的水平子午线（±10°、±20°、±25°）在远距（3 米）和近距（0.2 米）时的相对周边屈光度（RPR），以及在远距时垂直子午线（±10°、±15°）的 RPR 进行了测定。在未矫正状态以及单焦点眼镜、软性隐形眼镜和角膜塑形镜下获得了测量值。比较了不同模式下远距和近距观察时 RPR 和散光分量的变化。
在不同的屈光模式中，相对周边屈光度与目标距离（远距和近距）之间存在显著的相互作用（p = 0.02）。单独使用单夜角膜塑形术镜片会导致远距（平均 RPR ± SE：-0.92 ± 0.21D 和-1.04 ± 0.22D）和近距（-0.71 ± 0.17D 和-0.76 ± 0.20D）观察时的相对周边近视。在每个偏心度处，不同矫正方式之间的相对周边屈光度比较表明，在颞侧和鼻侧子午线的极端位置（±20°和±25°），RPR 具有统计学意义（p < 0.05）。软性隐形眼镜和眼镜在远距和近距观察时的 RPR 相似（p > 0.05）。
与单焦点眼镜和软性隐形眼镜相比，单独使用单夜角膜塑形术镜片会导致远距和近距观察时 RPR 向近视方向移动。角膜塑形术镜片设计提供大量的中周边角膜陡峭，进而导致远距和近距观察时的相对周边远视，这可能对近视控制有有益的效果。
