干细胞疗法及其在疼痛管理中的意义。
Stem Cell Therapy and Its Significance in Pain Management.
作者信息
Padda Jaskamal, Khalid Khizer, Zubair Ujala, Al Hennawi Hussam, Yadav Jayant, Almanie Abdulelah H, Mehta Krutagni Adwait, Tasnim Fahriba, Cooper Ayden Charlene, Jean-Charles Gutteridge
机构信息
Internal Medicine, JC Medical Center, Orlando, USA.
Internal Medicine, Avalon University School of Medicine, Willemstad, CUW.
出版信息
Cureus. 2021 Aug 17;13(8):e17258. doi: 10.7759/cureus.17258. eCollection 2021 Aug.
Pain management has always been a challenging issue, which is why it has been a major focus of many rigorous studies. Chronic pain which typically lasts for more than three months is prevalent at an astounding rate of 11% to 19% of the adult population. Pain management techniques have gone through major advances in the last decade with no major improvement in the quality of life in affected populations. Recently there has been growing interest in the utilization of stem cells for pain management. Advancement of stem cell therapy has been noted for the past few years and is now being used in human clinical trials. Stem cell therapy has shown promising results in the management of neuropathic, discogenic back, osteoarthritis, and musculoskeletal pain. In this article, we will discuss the role of stem cells in the pain management of the aforementioned conditions, along with the mechanism, adverse effects, and risks of stem cell therapy.
疼痛管理一直是一个具有挑战性的问题，这就是为什么它一直是许多严谨研究的主要焦点。慢性疼痛通常持续超过三个月，在成年人口中以惊人的11%至19%的比例普遍存在。在过去十年中，疼痛管理技术取得了重大进展，但受影响人群的生活质量却没有得到显著改善。最近，人们对利用干细胞进行疼痛管理的兴趣日益浓厚。在过去几年中，干细胞疗法已有进展，目前正在用于人体临床试验。干细胞疗法在治疗神经性、椎间盘源性背痛、骨关节炎和肌肉骨骼疼痛方面已显示出有希望的结果。在本文中，我们将讨论干细胞在上述疾病疼痛管理中的作用，以及干细胞疗法的机制、副作用和风险。
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