Departments of Emergency Medicine
Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Pediatrics. 2021 Oct;148(4). doi: 10.1542/peds.2020-045922. Epub 2021 Sep 20.
Canada legalized nonmedical cannabis possession and sale in October 2018. In the United States, state legalization has been tied to an increase in cannabis-related emergency department (ED) visits; however, little research exists on provincial changes in pediatric visits after nationwide legislation. We compared pre- and postlegalization trends in pediatric cannabis-related ED visits and presentation patterns in urban Alberta EDs.
Retrospective National Ambulatory Care Reporting System data were queried for urban Alberta cannabis-related ED visits among patients aged <18 years from October 1, 2013, to February 29, 2020. Population subgroups included children (aged 0-11 years), younger adolescents (12 to 14 years), and older adolescents (15 to 17 years). We calculated interrupted time series, incident rate ratios (IRRs), and relative risk (RR) ratios to identify trend change. IRRs identified changes against growth-adjusted Alberta population, while RRs measured presentation pattern changes against prelegalization ED visits.
Pediatric visit volume did not change postlegalization when accounting for preexisting volume trends. Unintentional ingestions increased in children (IRR: 1.77, 95% confidence interval [CI]: 1.42 to 2.20 and RR: 1.24, 95% CI: 1.05 to 1.47, respectively) and older adolescents (IRR: 1.36, 95% CI: 1.07 to 1.71 and RR: 1.48, 95% CI: 1.21 to 1.81, respectively). Presentation patterns remained similar, although older adolescent co-ingestant use decreased (RR: 0.77, 95% CI: 0.67 to 0.88), whereas hyperemesis cases increased (RR: 1.64, 95% CI: 1.13 to 2.37).
Cannabis legalization has increased child and older adolescent unintentional cannabis ingestions, increasing child cannabis-related ED visits. Changes highlight need for public health interventions targeting pediatric exposures.
加拿大于 2018 年 10 月将非医用大麻持有和销售合法化。在美国,州合法化与与大麻相关的急诊部(ED)就诊人数增加有关;然而,在全国范围内立法后,关于省级儿科就诊变化的研究甚少。我们比较了阿尔伯塔省城市 ED 中与儿科大麻相关的 ED 就诊和表现模式在法律颁布前后的趋势。
从 2013 年 10 月 1 日至 2020 年 2 月 29 日,使用国家门诊护理报告系统查询了阿尔伯塔省城市与大麻相关的<18 岁患者的 ED 就诊记录。人口亚组包括儿童(0-11 岁)、青少年(12-14 岁)和青少年(15-17 岁)。我们计算了中断时间序列、发病率比值(IRR)和相对风险(RR)比值,以确定趋势变化。IRR 针对增长调整后的阿尔伯塔省人口,而 RR 则针对法律颁布前的 ED 就诊,衡量就诊模式的变化。
在考虑到现有就诊量趋势后,法律颁布后儿科就诊量没有变化。儿童(IRR:1.77,95%置信区间[CI]:1.42 至 2.20 和 RR:1.24,95% CI:1.05 至 1.47,分别)和青少年(IRR:1.36,95% CI:1.07 至 1.71 和 RR:1.48,95% CI:1.21 至 1.81,分别)的非故意摄入有所增加。表现模式仍然相似,尽管青少年共服药物使用减少(RR:0.77,95% CI:0.67 至 0.88),而呕吐病例增加(RR:1.64,95% CI:1.13 至 2.37)。
大麻合法化增加了儿童和青少年非故意摄入大麻的情况,导致儿童与大麻相关的 ED 就诊增加。这些变化突出了针对儿科暴露的公共卫生干预措施的必要性。