Yeung Matthew E M, Weaver Colin G, Janz Kevin, Haines-Saah Rebecca, Lang Eddy
Department of Emergency Medicine, University of Calgary, Calgary, AB.
Department of Community Health Sciences, University of Calgary, Calgary, AB.
CJEM. 2020 Nov;22(6):776-783. doi: 10.1017/cem.2020.384.
Non-medical cannabis recently became legal for adults in Canada. Legalization provides opportunity to investigate the public health effects of national cannabis legalization on presentations to emergency departments (EDs). Our study aimed to explore association between cannabis-related ED presentations, poison control and telemedicine calls, and cannabis legalization.
Data were collected from the National Ambulatory Care Reporting System from October 1, 2013, to July 31, 2019, for 14 urban Alberta EDs, from Alberta poison control, and from HealthLink, a public telehealth service covering all of Alberta. Visitation data were obtained to compare pre- and post-legalization periods. An interrupted time-series analysis accounting for existing trends was completed, in addition to the incidence rate ratio (IRR) and relative risk calculation (to evaluate changes in co-diagnoses).
Although only 3 of every 1,000 ED visits within the time period were attributed to cannabis, the number of cannabis-related ED presentations increased post-legalization by 3.1 (range -11.5 to 12.6) visits per ED per month (IRR 1.45, 95% confidence interval [CI]; 1.39, 1.51; absolute level change: 43.5 visits per month, 95% CI; 26.5, 60.4). Cannabis-related calls to poison control also increased (IRR 1.87, 95% CI; 1.55, 2.37; absolute level change: 4.0 calls per month, 95% CI; 0.1, 7.9). Lastly, we observed increases in cannabis-related hyperemesis, unintentional ingestion, and individuals leaving the ED pre-treatment. We also observed a decrease in co-ingestant use.
Overall, Canadian cannabis legalization was associated with small increases in urban Alberta cannabis-related ED visits and calls to a poison control centre.
非医用大麻最近在加拿大对成年人合法化。合法化提供了一个机会来调查全国大麻合法化对急诊科就诊情况的公共卫生影响。我们的研究旨在探讨与大麻相关的急诊科就诊、中毒控制和远程医疗呼叫之间的关联,以及大麻合法化的影响。
收集了2013年10月1日至2019年7月31日期间艾伯塔省14个城市急诊科的全国门诊护理报告系统数据、艾伯塔省中毒控制数据以及覆盖整个艾伯塔省的公共远程医疗服务HealthLink的数据。获取就诊数据以比较合法化前后的时期。除了发病率比(IRR)和相对风险计算(以评估共诊断的变化)外,还完成了考虑现有趋势的中断时间序列分析。
尽管在此期间每1000次急诊科就诊中只有3次归因于大麻,但合法化后与大麻相关的急诊科就诊次数每个急诊科每月增加了3.1次(范围为-11.5至12.6次)(IRR为1.45,95%置信区间[CI];1.39,1.51;绝对水平变化:每月43.5次就诊,95%CI;26.5,60.4)。与大麻相关的中毒控制呼叫也增加了(IRR为1.87,95%CI;1.55,2.37;绝对水平变化:每月4.0次呼叫,95%CI;0.1,7.9)。最后,我们观察到与大麻相关的呕吐、意外摄入以及患者在治疗前离开急诊科的情况有所增加。我们还观察到同时摄入其他物质的情况有所减少。
总体而言,加拿大的大麻合法化与艾伯塔省城市地区与大麻相关的急诊科就诊次数和中毒控制中心呼叫次数的小幅增加有关。