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新型远端穿透性支架移植物治疗 B 型主动脉夹层的短期安全性和有效性:一项回顾性研究。

The short-term safety and effectiveness of a new distal perforating stent graft in Type B aortic dissection: a retrospective study.

机构信息

Vascular Intervention Department, Yan'an Hospital Affiliated to Kunming Medical University, Kunming, China.

The First School of Clinical Medicine, Yunnan University of Chinese Medicine, Yunnan, China.

出版信息

BMC Cardiovasc Disord. 2021 Sep 21;21(1):457. doi: 10.1186/s12872-021-02270-5.

DOI:10.1186/s12872-021-02270-5
PMID:34548009
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8456669/
Abstract

BACKGROUND

Spinal artery ischemia (SCI) events can result from over coverage of the descending thoracic aorta with a coated stent during Thoracic Endovascular Aortic Repair (TEVAR). The aim of this study was to determine whether a new distal perforating stent could reduce the incidence of spinal cord ischemia while remodeling the true lumen.

METHODS

TBAD patients treated with Talos stent in the vascular surgery Department of Yan 'an Hospital affiliated to Kunming Medical University between December 2017 and October 2019 were retrospectively analyzed to investigate the short-term safety and effectiveness of Talos stent.

RESULTS

A total of the 20 patients, including 14 males and 6 females, with an average age of 52.65 ± 8.98 years (range 37-68 years), were included in the analysis. Stent-grafts were successfully implanted in all patients under local anesthesia, with a technical success rate of 100%. The average operation time was 50.75 ± 13.01 min. A total of 2 cases (10%) presented chest pain associated with intercostal artery ischemia that was relieved on the 3rd and 5th postoperative day, respectively. Postoperative mean follow-up was 16.15 ± 3.99 months. No paraplegia or other complications occurred. And stenting did not induce new tears. No migration, deformation, or fracture of the stents occurred. There was a significant difference in the remolding of the true lumen preoperatively and at 12 months postoperatively (P < 0.05).

CONCLUSIONS

Talos stent has achieved satisfactory clinical treatment results in short term.

摘要

背景

在胸主动脉腔内修复术(TEVAR)中,涂层支架过度覆盖降主动脉可导致脊髓动脉缺血(SCI)事件。本研究旨在确定新型远端穿透性支架在重塑真腔的同时是否能降低脊髓缺血的发生率。

方法

回顾性分析 2017 年 12 月至 2019 年 10 月期间在昆明医科大学附属延安医院血管外科接受 Talos 支架治疗的胸主动脉夹层(TBAD)患者,以探讨 Talos 支架的短期安全性和有效性。

结果

共纳入 20 例患者,其中男性 14 例,女性 6 例,平均年龄 52.65±8.98 岁(37-68 岁)。所有患者均在局部麻醉下成功植入支架,技术成功率为 100%。平均手术时间为 50.75±13.01 分钟。共有 2 例(10%)患者出现胸痛合并肋间动脉缺血,分别于术后第 3 天和第 5 天缓解。术后平均随访 16.15±3.99 个月。无截瘫或其他并发症发生。支架置入也未导致新的撕裂。支架无迁移、变形或断裂。术前和术后 12 个月真腔重塑有显著差异(P<0.05)。

结论

Talos 支架在短期治疗中取得了满意的临床效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f84/8456669/39be40a6fbcb/12872_2021_2270_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f84/8456669/d660c702385d/12872_2021_2270_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f84/8456669/162aa1e30400/12872_2021_2270_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f84/8456669/112ed2625e08/12872_2021_2270_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f84/8456669/43bbb02dff9f/12872_2021_2270_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f84/8456669/6464a6613029/12872_2021_2270_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f84/8456669/39be40a6fbcb/12872_2021_2270_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f84/8456669/d660c702385d/12872_2021_2270_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f84/8456669/162aa1e30400/12872_2021_2270_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f84/8456669/112ed2625e08/12872_2021_2270_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f84/8456669/43bbb02dff9f/12872_2021_2270_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f84/8456669/6464a6613029/12872_2021_2270_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f84/8456669/39be40a6fbcb/12872_2021_2270_Fig6_HTML.jpg

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