Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA.
Weight Control and Diabetes Research Center, The Miriam Hospital, Providence, Rhode Island, USA.
Obesity (Silver Spring). 2021 Nov;29(11):1848-1856. doi: 10.1002/oby.23268. Epub 2021 Sep 21.
Recovery from weight regain is uncommon during weight loss treatment. This study examined whether participants in a weight gain prevention intervention similarly struggle to recover following weight gains and which factors predict transitions.
This is a secondary analysis of data from the Study of Novel Approaches to Weight Gain Prevention (SNAP), a randomized controlled trial comparing two weight gain prevention interventions with a control group. Young adults (n = 599; age 18-35 years) were followed over 3 years. Markov models identified transition rates in going above and returning below baseline weight across follow-up. Logistic regressions identified predictors of transitions.
At each time point, approximately double the number of participants who transitioned from below to above baseline transitioned from above to below. The magnitude of weight changes from baseline and the number of weight loss strategies used predicted transitions from below to above and above to below baseline weight (with opposite relationships). Infrequent self-weighing and lower dietary restraint predicted transitions below to above baseline weight. Treatment arm, demographics, calorie consumption, and physical activity generally did not predict transitions.
Young adults engaging in weight gain prevention struggle to lose gained weight. Alternative strategies are needed to address weight gains in weight gain prevention interventions.
在减肥治疗过程中，体重反弹后的恢复并不常见。本研究旨在探讨体重增加预防干预措施的参与者在体重增加后是否同样难以恢复，以及哪些因素可以预测体重的变化。
这是对预防体重增加新方法研究（SNAP）数据的二次分析，该研究是一项比较两种体重增加预防干预措施与对照组的随机对照试验。研究对象为年轻成年人（n=599；年龄 18-35 岁），随访时间为 3 年。马尔可夫模型确定了随访期间体重超过基线和恢复到基线以下的转变率。逻辑回归确定了转变的预测因素。
在每个时间点，从低于基线体重转变为高于基线体重的参与者数量是从高于基线体重转变为低于基线体重的参与者数量的两倍左右。从基线开始的体重变化幅度和使用的减肥策略数量预测了从低于基线体重到高于基线体重和从高于基线体重到低于基线体重的转变（呈相反关系）。不频繁自我称重和较低的饮食控制预测了从低于基线体重到高于基线体重的转变。治疗组、人口统计学因素、卡路里摄入量和身体活动通常不能预测体重的变化。
参与体重增加预防的年轻人在减肥方面遇到了困难。在体重增加预防干预措施中，需要采用替代策略来解决体重增加的问题。
