Nutrition and Metabolism Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Department of Computer Science and Biomedical Informatics, University of Thessaly, Lamia, Greece.
Methods Mol Biol. 2022;2345:173-185. doi: 10.1007/978-1-0716-1566-9_11.
Meta-analytic techniques are used to combine the results of different studies that have evaluated the accuracy of diagnostic tests. In this article, we present univariate and multivariate meta-analysis methods for a single test and we provide an extensive description of methods for meta-analysis and comparison of multiple diagnostic tests. We close with a practical example of a meta-analysis that aimed to determine whether Rheumatoid Factor identifies patients with Rheumatoid Arthritis.
元分析技术用于合并评估诊断测试准确性的不同研究的结果。在本文中，我们提出了用于单个测试的单变量和多变量元分析方法，并对元分析和多个诊断测试比较的方法进行了详细描述。最后，我们以一个旨在确定类风湿因子是否能识别类风湿关节炎患者的元分析为例。
