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1990-2017 年伊朗高血压性心脏病负担:2017 年全球疾病负担研究结果。

Burden of Hypertensive Heart Disease in Iran during 1990-2017: Findings from the Global Burden of Disease study 2017.

机构信息

Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.

Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran.

出版信息

PLoS One. 2021 Sep 22;16(9):e0257617. doi: 10.1371/journal.pone.0257617. eCollection 2021.

Abstract

BACKGROUND

Hypertension and its consequent end-organ damage including Hypertensive Heart Disease (HHD) are a major concern that impact health, resulting into impairment and reduced quality of life (QOL). The purpose of this study was to describe the burden of HHD in Iran and comparing it with the World Bank upper middle-income countries (UMICs) in terms of disability-adjusted life years (DALY), mortality and prevalence.

METHODS

Using data from the Global Burden of Disease study 2017, we compared the number of DALYs, deaths and prevalence trends for HHD from 1990 to 2017 in all age groups for both sex in Iran, and compared the epidemiology and trends with UMICs and globally.

RESULTS

The age-standardized DALY rate for HHD increased by 51.6% for men (95% uncertainty interval [UI] 305.8 to 436.7 per 100,000) and 4.4% for women (95% UI 429.4 to 448.7 per 100,000) in Iran. The age-standardized prevalence of HHD in Iran was almost twice times higher than globally and 1.5-times more than the World Bank UMICs. The age-standardized death rate for HDD increased by 60.1% (95% UI 17.3 to 27.7% per 100,000) for men and by 21.7% (95% UI 25.85 to 31.48 per 100,000) for women from 1990 to 2017. Age-standardized death rate in Iran was 2.4 and 1.9 times higher than globally and UMICs, respectively.

CONCLUSIONS

The higher prevalence and death rate in Iran in comparison with UMICs and globally should encourage health care provider to perform intensive screening activities in at risk population to prevent HHD and mitigate its mortality.

摘要

背景

高血压及其导致的终末器官损害,包括高血压性心脏病(HHD),是一个主要的健康问题,会导致身体残疾和生活质量下降。本研究的目的是描述伊朗 HHD 的负担,并在残疾调整生命年(DALY)、死亡率和患病率方面与世界银行上中等收入国家(UMICs)进行比较。

方法

使用 2017 年全球疾病负担研究的数据,我们比较了伊朗所有年龄段男女 HHD 的 DALY 数量、死亡人数和趋势,以及与 UMICs 和全球的流行病学和趋势。

结果

伊朗男性 HHD 的年龄标准化 DALY 率增加了 51.6%(95%置信区间 [UI] 305.8 至 436.7/每 10 万人),女性增加了 4.4%(95% UI 429.4 至 448.7/每 10 万人)。伊朗 HHD 的年龄标准化患病率几乎是全球的两倍,是世界银行 UMICs 的 1.5 倍。伊朗 HHD 的年龄标准化死亡率男性增加了 60.1%(95% UI 17.3 至 27.7/每 10 万人),女性增加了 21.7%(95% UI 25.85 至 31.48/每 10 万人)。伊朗的年龄标准化死亡率分别是全球和 UMICs 的 2.4 和 1.9 倍。

结论

与 UMICs 和全球相比,伊朗的患病率和死亡率较高,应鼓励医疗保健提供者在高危人群中开展强化筛查活动,以预防 HHD 并降低其死亡率。

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