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无菌性翻修全髋关节置换术后患者报告的结局指标会改善吗?

Do patient-reported outcome measures improve after aseptic revision total hip arthroplasty?

作者信息

Siddiqi Ahmed, Warren Jared, Anis Hiba K, Barsoum Wael K, Bloomfield Michael R, Briskin Isaac, Brooks Peter J, Higuera Carlos A, Kamath Atul F, Klika Alison, Krebs Olivia, Krebs Viktor E, Mesko Nathan W, Molloy Robert M, Mont Michael A, Murray Trevor G, Muschler George F, Patel Preetesh, Stearns Kim L, Strnad Gregory J, Suarez Juan C, Piuzzi Nicolas S

机构信息

Orthopaedic Department, Cleveland Clinic Foundation, Cleveland, OH, USA.

Cleveland Clinic Department of Quantitative Health Sciences, Cleveland, OH, USA.

出版信息

Hip Int. 2023 Mar;33(2):267-279. doi: 10.1177/11207000211036320. Epub 2021 Sep 23.

DOI:10.1177/11207000211036320
PMID:34554849
Abstract

BACKGROUND

The purpose of this study was to determine patient-reported outcome measures (PROMs) changes in: (1) pain, function and global health; and (2) predictors of PROMs in patients undergoing aseptic revision total hip arthroplasty (rTHA) using a multilevel model with patients nested within surgeon.

METHODS

A prospective cohort of 216 patients with baseline and 1-year PROMs who underwent aseptic rTHA between January 2016 and December 2017 were analysed. The most common indication for rTHA was aseptic loosening, instability, and implant failure. The PROMs included in this study were HOOS Pain and HOOS Physical Function Short-form (PS), Veterans RAND-12 Physical Component Score (VR-12 PCS), and VR-12 Mental Component Score (MCS). Multivariable linear regression models were constructed for predicting 1-year PROMs.

RESULTS

Mean 1-year PROMs improvement for aseptic revisions were 30.4 points for HOOS Pain and 22.1 points for HOOS PS. Predictors of better pain relief were patients with higher baseline pain scores. Predictors of better 1-year function were patients with higher baseline function and patients with a posterolateral hip surgical approach during revision. Although VR-12 PCS scores had an overall improvement, nearly 50% of patients saw no improvement or had worse physical component scores. Only 30.7% of patients reported improvements in VR-12 MCS.

CONCLUSIONS

Overall, patients undergoing aseptic rTHA improved in pain and function PROMs at 1 year. Although global health assessment improved overall, nearly half of aseptic rTHA patients reported no change in physical/mental health status. The associations highlighted in this study can help guide the shared decision-making process by setting expectations before aseptic revision THA.

摘要

背景

本研究的目的是确定患者报告结局指标(PROMs)在以下方面的变化:(1)疼痛、功能和总体健康状况;(2)采用患者嵌套于外科医生的多层次模型,对接受无菌性翻修全髋关节置换术(rTHA)患者的PROMs预测因素进行研究。

方法

分析了2016年1月至2017年12月期间接受无菌性rTHA且有基线和1年PROMs数据的216例患者的前瞻性队列。rTHA最常见的适应证是无菌性松动、不稳定和植入物失败。本研究纳入的PROMs包括全髋关节置换术患者疼痛评分(HOOS Pain)、全髋关节置换术患者身体功能简表(HOOS PS)、退伍军人兰德12项身体成分评分(VR-12 PCS)和退伍军人兰德12项心理成分评分(VR-12 MCS)。构建多变量线性回归模型来预测1年的PROMs。

结果

无菌性翻修术后1年,HOOS Pain平均改善30.4分,HOOS PS平均改善22.1分。疼痛缓解较好的预测因素是基线疼痛评分较高的患者。1年功能改善较好的预测因素是基线功能较高的患者以及翻修期间采用后外侧髋关节手术入路的患者。虽然VR-12 PCS评分总体有所改善,但近50%的患者没有改善或身体成分评分更差。只有30.7%的患者报告VR-12 MCS有所改善。

结论

总体而言,接受无菌性rTHA的患者在1年时疼痛和功能PROMs有所改善。虽然总体健康评估有所改善,但近一半的无菌性rTHA患者报告其身体/心理健康状况没有变化。本研究中强调的关联有助于在无菌性翻修全髋关节置换术前设定预期,从而指导共同决策过程。

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