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2021 年 7 月至 8 月,德克萨斯州一联邦监狱中被监禁人员感染 SARS-CoV-2 B.1.617.2(Delta)变异株疫情。

Outbreak of SARS-CoV-2 B.1.617.2 (Delta) Variant Infections Among Incarcerated Persons in a Federal Prison - Texas, July-August 2021.

出版信息

MMWR Morb Mortal Wkly Rep. 2021 Sep 24;70(38):1349-1354. doi: 10.15585/mmwr.mm7038e3.

DOI:10.15585/mmwr.mm7038e3
PMID:34555009
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8459894/
Abstract

Incarcerated populations have experienced disproportionately higher rates of COVID-19-related illness and death compared with the general U.S. population, due in part to congregate living environments that can facilitate rapid transmission of SARS-CoV-2, the virus that causes COVID-19, and the high prevalence of underlying medical conditions associated with severe COVID-19 (1,2). The SARS-CoV-2 B.1.617.2 (Delta) variant has caused outbreaks among vaccinated and unvaccinated persons in congregate settings and large public gatherings (3,4). During July 2021, a COVID-19 outbreak involving the Delta variant was identified in a federal prison in Texas, infecting 172 of 233 (74%) incarcerated persons in two housing units. The Federal Bureau of Prisons (BOP) partnered with CDC to investigate. CDC analyzed data on infection status, symptom onset date, hospitalizations, and deaths among incarcerated persons. The attack rate was higher among unvaccinated versus fully vaccinated persons (39 of 42, 93% versus 129 of 185, 70%; p = 0.002). Four persons were hospitalized, three of whom were unvaccinated, and one person died, who was unvaccinated. Among a subset of 70 persons consenting to an embedded serial swabbing protocol, the median interval between symptom onset and last positive reverse transcription-polymerase chain reaction (RT-PCR) test result in fully vaccinated versus unvaccinated persons was similar (9 versus 11 days, p = 0.37). One or more specimens were culture-positive from five of 12 (42%) unvaccinated and 14 of 37 (38%) fully vaccinated persons for whom viral culture was attempted. In settings where physical distancing is challenging, including correctional and detention facilities, vaccination and implementation of multicomponent prevention strategies (e.g., testing, medical isolation, quarantine, and masking) are critical to limiting SARS-CoV-2 transmission (5).

摘要

监禁人口与美国普通人群相比,COVID-19 相关疾病和死亡的比例过高,部分原因是集中居住环境有利于 SARS-CoV-2 的快速传播,SARS-CoV-2 是导致 COVID-19 的病毒,以及与 COVID-19 严重程度相关的高发基础疾病(1,2)。SARS-CoV-2 B.1.617.2(Delta)变体已在接种疫苗和未接种疫苗的人群中在集中居住环境和大型公共集会中引起爆发(3,4)。2021 年 7 月,在德克萨斯州的一个联邦监狱中发现了涉及 Delta 变体的 COVID-19 爆发,感染了两个住房单元中 233 名囚犯中的 172 名(74%)。联邦监狱局(BOP)与疾病预防控制中心合作进行调查。疾病预防控制中心分析了囚犯感染状况,症状发作日期,住院和死亡的数据。与完全接种疫苗的人相比,未接种疫苗的人的发病率更高(39/42,93%对 185/185,70%;p=0.002)。有 4 人住院,其中 3 人未接种疫苗,1 人死亡,未接种疫苗。在同意纳入嵌入式连续拭子采集方案的 70 人亚组中,完全接种疫苗与未接种疫苗的人之间症状发作与最后一次阳性逆转录聚合酶链反应(RT-PCR)检测结果之间的中位数间隔相似(9 天对 11 天,p=0.37)。尝试进行病毒培养的 12 名未接种疫苗者中的 5 名(42%)和 37 名完全接种疫苗者中的 14 名(38%)的一个或多个标本培养阳性。在包括惩教和拘留设施在内的物理距离难以保持的环境中,接种疫苗和实施多组分预防策略(例如检测、医学隔离、检疫和戴口罩)对于限制 SARS-CoV-2 的传播至关重要(5)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed50/8459894/662f561402ed/mm7038e3-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed50/8459894/662f561402ed/mm7038e3-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed50/8459894/662f561402ed/mm7038e3-F.jpg

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