Division of Endocrinology, Diabetes and Metabolism, VA New York Harbor Healthcare System, NYU Grossman School of Medicine, New York, NY, United States.
Front Endocrinol (Lausanne). 2021 Sep 7;12:752329. doi: 10.3389/fendo.2021.752329. eCollection 2021.
Evidence from populations at risk for type 1 diabetes, type 2 diabetes or gestational diabetes substantiates the 1-hour plasma glucose as a sensitive alternative marker for identifying high-risk individuals when ß-cell function is relatively more functional. An elevated 1-hour plasma glucose could therefore diagnose dysglycemia and risk for complications across the glycemic spectrum. Reducing the 2-hour oral glucose tolerance test to 1-hour would reduce the burden on patients, likely reduce costs, and enhance its accessibility in practice.
来自于 1 型糖尿病、2 型糖尿病或妊娠糖尿病高危人群的证据表明,当β细胞功能相对更具功能性时,1 小时血浆葡萄糖是识别高危个体的敏感替代标志物。因此,升高的 1 小时血浆葡萄糖可以诊断血糖异常和整个血糖谱的并发症风险。将 2 小时口服葡萄糖耐量试验缩短至 1 小时将减轻患者负担,可能降低成本,并增强其实践中的可及性。