Chávez-Pérez Carlos, Jafari Niusha, Keenan Brendan T, Raizen David M, Rohacek Alex M
Department of Neurology, Perelman School of Medicine, University of Pennsylvania.
Division of Sleep Medicine, Department of Medicine, Perelman School of Medicine, University of Pennsylvania.
MicroPubl Biol. 2021 Sep 20;2021. doi: 10.17912/micropub.biology.000468. eCollection 2021.
The interneurons ALA and RIS both regulate stress induced sleep in but their roles in awake animal movement has been reported to differ. We describe the development of a motivated mobility-based assay that distinguishes between animals mutant for ALA function and those mutant for RIS function.
中间神经元ALA和RIS都调节应激诱导的睡眠,但据报道它们在清醒动物运动中的作用有所不同。我们描述了一种基于动机性移动的检测方法的开发,该方法可以区分ALA功能突变的动物和RIS功能突变的动物。