Department of Radiology, Seoul National University Bunding Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea.
Medicine (Baltimore). 2021 Sep 24;100(38):e27243. doi: 10.1097/MD.0000000000027243.
To compare the performance of margin assessment of specimen mammography (SM) in patients with breast-conserving surgery (BCS) on mobile devices and 5-megapixel (5M) thin film transistor liquid crystal display (TFT-LCD) monitors based on the safety margin for pathologic results.This retrospective study was approved by the institutional review board, and the requirement for informed consent was waived. A total of 105 consecutive breast cancer SM samples from 104 women who underwent BCS were included in the study. The SM were independently reviewed by two radiologists using mobile devices and by two additional radiologists using 5M TFT-LCD monitor. Each reader was asked to measure the shortest distance between the lesion and the lesion margin. The interpretation time was recorded. The sensitivity, specificity, and interobserver agreement were analyzed.In total, 19% (20/105) breast specimens had a positive surgical margin (<1 mm). The mean absolute difference from the pathologic margin was 0.60 ± 0.57 cm and 0.54 ± 0.47 cm using the 5 M TFT-LCD monitor and the mobile device, respectively (without any statistical significance, P = .273). The mean interpretation time was 49.5 and 47.6 s for the 5M TFT-LCD monitor and the mobile device, respectively (P = .012). The pooled sensitivity and specificity were 60% and 74% for 5M TFT-LCD monitor, and 60% and 69% for the mobile device (P = 1.00 and P = .190, respectively). The kappa coefficient indicated moderate agreement for both the displays.The diagnostic performance for margin assessment of SM in BCS patients on mobile devices and 5M TFT-LCD monitors are showed not statistically difference. The findings of the study provide evidence of the benefit of the mobile device for SM interpretation in patients who underwent BCS. However, a large sample size study is warranted before using a mobile device for margin evaluation on SM.The mobile device showed comparable diagnostic performance with 5M TFT-LCD monitor in the evaluation of SM margin in patients with BCS and could be used as a display tool for immediate assessment when a dedicated LCD monitor is unavailable.
为了比较在保乳手术后（BCS）患者中使用移动设备和 5 兆像素（5M）薄膜晶体管液晶显示器（TFT-LCD）评估切缘的表现，基于病理结果安全切缘。这项回顾性研究得到了机构审查委员会的批准，并免除了知情同意的要求。共纳入 104 例接受 BCS 的乳腺癌 SM 标本 105 例。两位放射科医生使用移动设备，另外两位放射科医生使用 5M TFT-LCD 显示器独立对 SM 进行了评估。每位读者均被要求测量病变与病变边缘之间的最短距离。记录解释时间。分析了敏感性、特异性和观察者间一致性。共有 19%（20/105）的乳腺标本切缘阳性（<1mm）。使用 5M TFT-LCD 显示器和移动设备测量的病理切缘的平均绝对差值分别为 0.60±0.57cm 和 0.54±0.47cm（无统计学意义，P=0.273）。使用 5M TFT-LCD 显示器和移动设备的平均解释时间分别为 49.5 和 47.6s（P=0.012）。5M TFT-LCD 显示器的总体敏感性和特异性分别为 60%和 74%，移动设备分别为 60%和 69%（P=1.00 和 P=0.190）。kappa 系数表明两种显示器的一致性为中度。在 BCS 患者的 SM 边缘评估中，移动设备和 5M TFT-LCD 显示器的诊断性能无统计学差异。该研究结果为移动设备在接受 BCS 的患者的 SM 解读中提供了有益的证据。然而，在使用移动设备进行 SM 边缘评估之前，需要进行更大的样本量研究。移动设备在 BCS 患者的 SM 边缘评估中与 5M TFT-LCD 显示器具有相当的诊断性能，在专用的 LCD 显示器不可用时，可作为即时评估的显示工具。
