Huang Shiqi, Zhang Dongdong, Li Yuze, Fan Hao, Liu Yuanyuan, Huang Wenli, Deng Chong, Wang Wei, Song Xiaomei
School of Pharmacy, Shaanxi University of Chinese Medicine, Xian Yang, Shaanxi 712046, P. R. China.
Am J Chin Med. 2021;49(7):1577-1622. doi: 10.1142/S0192415X21500749. Epub 2021 Sep 23.
Rehd. et Wils () is a single species of genus, family, and it is a famous medicinal herb mostly growing in southern China, China Taiwan and Vietnam. is usually used for the treatments of hepatitis, Alzheimer's disease, renal transplantation, osteoporosis, and insomnia. In present studies, approximately 310 natural constituents have been isolated from , including lignans, triterpenes, volatile oils, and polysaccharides, which were mainly obtained from the fruits and stems of . Pharmocological studies have shown that the extracts and monomeric compounds of possessed wide-range bioactivities, such as antitumor, anti-oxidant, anti-inflammatory, osteoblastic, immune regulation, neuroprotective, kidney protection, hepatoprotective, and antiviral activities. However, resource availability, quality control measures, in-depth pharmacological study, and clinical application are still insufficient and deserve further studies. This review systematically summarized literatures on the botany, phytochemistry, pharmacology, development utilization, and clinical application of , in hopes of provide a useful reference for researchers for further studies of this plant.
Rehd. et Wils（）是某属、某科的单一物种，是一种著名的药用植物，主要生长在中国南方、中国台湾和越南。它通常用于治疗肝炎、阿尔茨海默病、肾移植、骨质疏松症和失眠。在目前的研究中，已从该植物中分离出约310种天然成分，包括木脂素、三萜类、挥发油和多糖，这些成分主要从该植物的果实和茎中获得。药理学研究表明，该植物的提取物和单体化合物具有广泛的生物活性，如抗肿瘤、抗氧化、抗炎、成骨、免疫调节、神经保护、肾脏保护、肝脏保护和抗病毒活性。然而，资源可得性、质量控制措施、深入的药理学研究和临床应用仍然不足，值得进一步研究。本综述系统总结了关于该植物的植物学、植物化学、药理学、开发利用和临床应用的文献，希望为研究人员进一步研究这种植物提供有用的参考。
