Silverthorn K G, Gillespie W J
N Z Med J. 1986 Feb 12;99(795):62-5.
The presentation and outcome of 61 cases of nontuberculous spinal osteomyelitis were reviewed. Although the commonest presentation was subacute, with back pain predominating, 10% had septicaemia and 7% paraperesis or paraplegia. Most infections were caudal to the fourth thoracic vertebra. One third were associated with preceding urinary, respiratory, dental or abdominal sepsis. Staphylococcus aureus was the infecting organism in 85% of isolates. Delay in diagnosis was frequent. There were four deaths, and seven individuals remained severely disabled: outcome was otherwise satisfactory. An algorithm for the investigation and management of this uncommon but serious condition is proposed.
对61例非结核性脊柱骨髓炎的临床表现及治疗结果进行了回顾。尽管最常见的表现为亚急性,以背痛为主,但10%的患者有败血症,7%有下肢轻瘫或截瘫。大多数感染发生在第四胸椎以下。三分之一的病例与先前的泌尿道、呼吸道、牙科或腹部败血症有关。85%的分离株中感染病原体为金黄色葡萄球菌。诊断延误很常见。有4例死亡,7例仍严重残疾:其他患者的治疗结果令人满意。本文提出了针对这种罕见但严重疾病的调查及处理流程。