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化脓性脊椎骨髓炎:61例病例回顾

Pyogenic spinal osteomyelitis: a review of 61 cases.

作者信息

Silverthorn K G, Gillespie W J

出版信息

N Z Med J. 1986 Feb 12;99(795):62-5.

PMID:3456113
Abstract

The presentation and outcome of 61 cases of nontuberculous spinal osteomyelitis were reviewed. Although the commonest presentation was subacute, with back pain predominating, 10% had septicaemia and 7% paraperesis or paraplegia. Most infections were caudal to the fourth thoracic vertebra. One third were associated with preceding urinary, respiratory, dental or abdominal sepsis. Staphylococcus aureus was the infecting organism in 85% of isolates. Delay in diagnosis was frequent. There were four deaths, and seven individuals remained severely disabled: outcome was otherwise satisfactory. An algorithm for the investigation and management of this uncommon but serious condition is proposed.

摘要

对61例非结核性脊柱骨髓炎的临床表现及治疗结果进行了回顾。尽管最常见的表现为亚急性,以背痛为主,但10%的患者有败血症,7%有下肢轻瘫或截瘫。大多数感染发生在第四胸椎以下。三分之一的病例与先前的泌尿道、呼吸道、牙科或腹部败血症有关。85%的分离株中感染病原体为金黄色葡萄球菌。诊断延误很常见。有4例死亡,7例仍严重残疾:其他患者的治疗结果令人满意。本文提出了针对这种罕见但严重疾病的调查及处理流程。

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Pyogenic spinal osteomyelitis: a review of 61 cases.化脓性脊椎骨髓炎:61例病例回顾
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引用本文的文献

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A case of atypical presentation of thoracic osteomyelitis & paraspinal abscess.一例胸椎骨髓炎及椎旁脓肿的非典型表现病例。
Mcgill J Med. 2008 Jul;11(2):164-7.
2
Vertebral osteomyelitis caused by group B streptococci (Streptococcus agalactiae) secondary to urinary tract infection.由B组链球菌(无乳链球菌)引起的继发于尿路感染的脊椎骨髓炎。
Eur J Clin Microbiol Infect Dis. 1997 Mar;16(3):244-6. doi: 10.1007/BF01709590.
3
Pyogenic vertebral osteomyelitis of the posterior elements.
Skeletal Radiol. 1989;18(3):175-8. doi: 10.1007/BF00360963.
4
Staphylococcus aureus meningitis from osteomyelitis of the spine.由脊柱骨髓炎引起的金黄色葡萄球菌性脑膜炎。
Postgrad Med J. 1989 Dec;65(770):941-2. doi: 10.1136/pgmj.65.770.941.
5
Vertebral osteomyelitis presenting with pleuritic chest pain and bilateral pleural effusions.以胸膜炎性胸痛和双侧胸腔积液为表现的椎体骨髓炎。
Thorax. 1992 May;47(5):395-6. doi: 10.1136/thx.47.5.395.