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血红蛋白和血细胞比容水平与 10 至 18 岁儿童和青少年的血压呈正相关。

Hemoglobin and hematocrit levels are positively associated with blood pressure in children and adolescents 10 to 18 years old.

机构信息

Department of Pediatrics, College of Medicine, Soonchunhyang University, Cheonan Hospital, Cheonan-si, Korea.

Department of Pediatrics, Ajou University Hospital, Ajou University School of Medicine, 164 World cup-ro, Yeongtong-gu, Suwon, 16499, Korea.

出版信息

Sci Rep. 2021 Sep 24;11(1):19052. doi: 10.1038/s41598-021-98472-0.

Abstract

To investigate the associations between hemoglobin (Hb) concentration and hematocrit (Hct), and blood pressure (BP) in children and adolescents. The study population consisted of 7950 subjects total (4229 boys and 3721 girls) aged 10-18 years who participated in the Korea National Health and Nutrition Examination Surveys conducted between 2007 and 2017. The prevalence of hypertension was 19.19% (21.51% for boys and 16.5% for girls) among the study population, and the prevalence of obesity was 9.59% (10.5% for boys and 8.6% for girls). Hb count and Hct tended to increase with the degree of obesity and BP elevation. Systolic BP (SBP) and diastolic BP (DBP) positively correlated with Hb count and Hct in both sexes. Following multiple linear regression analysis, Hb count and Hct presented a positive association with SBP and DBP after adjusting for age, BMI SDS, alcohol consumption, smoking status, physical activity, rural residence, household income, diagnosis of T2DM, hypertension, and dyslipidemia. Hb count and Hct were positively associated with SBP and DBP in children and adolescents 10-18 years old.

摘要

目的

探讨儿童和青少年血红蛋白(Hb)浓度和红细胞压积(Hct)与血压(BP)之间的相关性。

方法

研究人群为 2007 年至 2017 年期间参加韩国国家健康和营养检查调查的 7950 名年龄在 10-18 岁的受试者(男 4229 名,女 3721 名)。研究人群中高血压的患病率为 19.19%(男 21.51%,女 16.5%),肥胖的患病率为 9.59%(男 10.5%,女 8.6%)。Hb 计数和 Hct 随着肥胖程度和 BP 升高而升高。SBP 和 DBP 与 Hb 计数和 Hct 在两性中均呈正相关。经过多元线性回归分析,在校正年龄、BMI SDS、饮酒、吸烟状况、体力活动、农村居住、家庭收入、T2DM、高血压和血脂异常的诊断后,Hb 计数和 Hct 与 SBP 和 DBP 呈正相关。

结果

Hb 计数和 Hct 与 10-18 岁儿童和青少年的 SBP 和 DBP 呈正相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1626/8463603/e8bf8124edee/41598_2021_98472_Fig1_HTML.jpg

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