Nickels Matt, Mastana Sarabjit, Codd Veryan, Denniff Matthew, Akam Elizabeth
School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough,United Kingdom.
Department of Cardiovascular Sciences, University of Leicester, Leicester,United Kingdom.
J Aging Phys Act. 2022 Jun 1;30(3):510-516. doi: 10.1123/japa.2021-0236. Epub 2021 Sep 25.
It is unclear how running modality influences telomere length (TL). This single laboratory visit study compared the TL of master sprinters and endurance runners with their young counterparts. The correlation between leukocyte and buccal cell TL in athletes was also explored. Participants consisted of 11 young controls, 11 young sprinters, 12 young endurance runners, 12 middle-aged controls, 11 master sprinters, and 12 master endurance runners. Blood and buccal samples were collected and randomized for analysis of TL by quantitative polymerase chain reaction. Young endurance runners displayed longer telomeres than master athletes (p < .05); however, these differences were not significant when controlled for covariates (p > .05). A positive correlation existed between leukocyte and buccal cell TL in athletes (r = .567, p < .001). In conclusion, young endurance runners possess longer telomeres than master endurance runners and sprinters, a consequence of lower body mass index and visceral fat.
目前尚不清楚跑步方式如何影响端粒长度（TL）。这项单次实验室访视研究比较了短跑健将和耐力跑运动员与年轻对照者的端粒长度。同时还探究了运动员白细胞端粒长度与颊细胞端粒长度之间的相关性。参与者包括11名年轻对照者、11名年轻短跑运动员、12名年轻耐力跑运动员、12名中年对照者、11名短跑健将和12名耐力跑健将。采集血液和颊部样本并随机分组，通过定量聚合酶链反应分析端粒长度。年轻耐力跑运动员的端粒比资深运动员更长（p < 0.05）；然而，在对协变量进行控制后，这些差异并不显著（p > 0.05）。运动员的白细胞端粒长度与颊细胞端粒长度之间存在正相关（r = 0.567，p < 0.001）。总之，年轻耐力跑运动员的端粒比资深耐力跑运动员和短跑健将更长，这是较低体重指数和内脏脂肪的结果。
