正念冥想期间迟发性运动障碍的改善
Improvement of Tardive Dyskinesia during Mindfulness Meditation.
作者信息
Santoro Maria Angela, English Isolde, Sezer Idil, Amagat Mickael, Ly Frank, Chaneac Edouard, Cailliez Patricia, Bottemanne Hugo
机构信息
Department of Psychiatry, Pitié-Salpêtrière Hospital, DMU Neuroscience, Sorbonne University, Assistance Publique-Hôpitaux de Paris (AP-HP), 75651 Paris, France.
Paris Brain Institute-Institut du Cerveau (ICM), Sorbonne University/CNRS/INSERM, UMR 7225/UMRS 1127, 75651 Paris, France.
出版信息
Neurol Int. 2021 Aug 30;13(3):439-444. doi: 10.3390/neurolint13030043.
BACKGROUND
We report the case of a patient presenting with orofacial tardive dyskinesia (TD), following administration of a first-generation antipsychotic (Loxapine).
INTERVENTION
Four weeks of repeated sessions of mindfulness-based cognitive therapy (MBCT) and mindfulness-based stress reduction (MBSR) protocols were administered, with TD hetero-quantified before and during each session via the Abnormal Involuntary Movement Scale (AIMS).
RESULTS
The dyskinesia ameliorated quantitatively and qualitatively (1) during each session, and (2) at resting conditions in the long term. During some sessions, after which patients' compliance was auto-evaluated as maximal, complete arrest of the TD was observed. Hypothesis and Conclusion: We suggest mindfulness meditation as a novel adjunctive therapeutic approach for tardive dyskinesia, and invite for further clinical and neurological investigations.
背景
我们报告了一例在服用第一代抗精神病药物（洛沙平）后出现口面部迟发性运动障碍（TD）的患者病例。
干预措施
进行了为期四周的基于正念的认知疗法（MBCT）和基于正念的减压疗法（MBSR）的重复疗程，在每个疗程之前和期间通过异常不自主运动量表（AIMS）对TD进行异质性量化。
结果
（1）在每个疗程期间，以及（2）长期处于静息状态时，运动障碍在数量和质量上均有所改善。在某些疗程中，患者自我评估为依从性最佳，之后观察到TD完全停止。假设与结论：我们建议将正念冥想作为迟发性运动障碍的一种新型辅助治疗方法，并呼吁进行进一步的临床和神经学研究。
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