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鼻窦炎后作为颅内并发症的脑实质脓肿

Parenchymal Brain Abscess as an Intracranial Complication After Sinusitis.

作者信息

Michali Maria C, Kastanioudakis Ioannis G, Basiari Lentiona V, Alexiou Georgios, Komnos Ioannis D

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Ioannina, Ioannina, GRC.

Department of Neurosurgery, University Hospital of Ioannina, Ioannina, GRC.

出版信息

Cureus. 2021 Aug 22;13(8):e17365. doi: 10.7759/cureus.17365. eCollection 2021 Aug.

Abstract

Brain abscesses caused by sinusitis are rare in the antibiotic era. The purpose of the current manuscript was to report a rare case of a brain abscess located mainly in the frontal lobe after sinusitis, which was initially thought to be meningitis or encephalitis. A 39-year-old man was transferred to our hospital from another neighbouring hospital with tonic-clonic seizures, severe headache, and purulent nasal secretions. For one week, he was taking antibiotics for sinusitis. The computed tomography indicated lesions in the right sinuses but not in the parenchymal brain and thus antibiotics along with antiepileptic drugs were given. However, due to the deterioration of symptoms, magnetic resonance imaging was executed, which revealed an abscess in the frontal lobe. Afterward, an anterior ethmoidectomy and middle maxillary antrostomy were performed in order to drain the purulent content from the right sinuses. Ten days later, the patient presented disorientation and thus an open craniotomy for successful removal of the parenchymal abscess was performed. One month later, the patient was discharged with mild irritability, which was eliminated gradually over the next two months. Conclusively, brain abscesses can be caused by local spread from an infection of the paranasal sinus. The contribution of imaging modality is very significant not only for the early diagnosis but also for the therapeutic management of such cases. Frequently antibiotic treatment is insufficient and surgery may be required.

摘要

在抗生素时代,鼻窦炎引起的脑脓肿较为罕见。本论文的目的是报告一例罕见的鼻窦炎后脑脓肿病例,该脓肿主要位于额叶,最初被误诊为脑膜炎或脑炎。一名39岁男性从邻近医院转至我院,伴有强直阵挛性癫痫发作、严重头痛和脓性鼻分泌物。他因鼻窦炎服用抗生素已有一周时间。计算机断层扫描显示右侧鼻窦有病变,但脑实质未见异常,因此给予了抗生素和抗癫痫药物治疗。然而,由于症状恶化,进行了磁共振成像检查,结果显示额叶有一个脓肿。随后,实施了前筛窦切除术和上颌窦中鼻道开窗术,以引流右侧鼻窦的脓性分泌物。十天后,患者出现定向障碍,因此进行了开颅手术,成功切除了脑实质内的脓肿。一个月后,患者出院,仍有轻度易怒症状,在接下来的两个月内逐渐消失。总之,脑脓肿可由鼻窦感染局部蔓延引起。影像学检查不仅对早期诊断,而且对此类病例的治疗管理都具有非常重要的作用。抗生素治疗往往不足,可能需要手术治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a52/8454594/617d4d625195/cureus-0013-00000017365-i01.jpg

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