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鼻窦炎的颅内化脓性并发症

Intracranial Suppurative Complications of Sinusitis.

作者信息

Nicoli T K, Oinas M, Niemelä M, Mäkitie A A, Atula T

机构信息

1 Department of Otorhinolaryngology-Head and Neck Surgery, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.

2 Department of Neurosurgery, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.

出版信息

Scand J Surg. 2016 Dec;105(4):254-262. doi: 10.1177/1457496915622129. Epub 2016 Jun 22.

Abstract

BACKGROUND

Intracranial complications of paranasal sinusitis have become rare due to widespread and early use of antibiotics. Potentially life-threatening intracranial complications of sinusitis include subdural empyema, epidural and intracerebral abscess, meningitis, and sinus thrombosis. Patients with intracranial complication of sinusitis can present without neurological signs, which may delay diagnosis and correct treatment.

AIMS

Our aim was to evaluate the diagnostics, treatment, and outcome of sinusitis-related intracranial infections at our tertiary referral hospital with a catchment area of 1.9 million people.

MATERIALS AND METHODS

We retrospectively collected data on all patients diagnosed and treated with an intracranial infection at the Helsinki University Hospital, Helsinki, Finland, during a 10-year period between 2003 and 2013.

RESULTS

Six patients were diagnosed to have a sinusitis-related intracranial infection. Four patients had an epidural abscess, one both an epidural abscess and a subdural empyema and one a subdural empyema. The most common presenting complaint was headache (100%) followed by fever (83%), vomiting (50%), nasal congestion (50%), forehead lump (34%), and neck stiffness (17%). All patients were managed surgically. Most (83%) patients recovered to premorbid state without neurological sequelae. One patient died intraoperatively.

CONCLUSION

Patients with a sinusitis-related intracranial suppuration typically present with signs of raised intracranial pressure rather than signs of sinusitis. Most are likely to need neurosurgical intervention and evacuation of the abscess without delay.

摘要

背景

由于抗生素的广泛早期使用,鼻窦炎的颅内并发症已变得罕见。鼻窦炎潜在的危及生命的颅内并发症包括硬膜下积脓、硬膜外和脑内脓肿、脑膜炎及鼻窦血栓形成。鼻窦炎颅内并发症患者可能无神经系统体征,这可能会延迟诊断和正确治疗。

目的

我们的目的是评估在我们这家服务人口达190万的三级转诊医院中,鼻窦炎相关颅内感染的诊断、治疗及转归情况。

材料与方法

我们回顾性收集了2003年至2013年这10年间在芬兰赫尔辛基大学医院诊断并治疗的所有颅内感染患者的数据。

结果

6例患者被诊断为鼻窦炎相关颅内感染。4例患者有硬膜外脓肿,1例既有硬膜外脓肿又有硬膜下积脓,1例有硬膜下积脓。最常见的主诉是头痛(100%),其次是发热(83%)、呕吐(50%)、鼻塞(50%)、额部肿块(34%)和颈部僵硬(17%)。所有患者均接受了手术治疗。大多数(83%)患者恢复到病前状态,无神经后遗症。1例患者术中死亡。

结论

鼻窦炎相关颅内化脓患者通常表现为颅内压升高的体征而非鼻窦炎体征。大多数患者可能需要神经外科干预并及时引流脓肿。

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