[霍乱弧菌中决定肠毒素合成的调节基因的遗传图谱]
[Genetic mapping of the regulatory gene determining the synthesis of enterotoxin in Vibrio cholerae].
作者信息
Smirnova N I, Livanova L F, Shaginian I A, Motin V L
出版信息
Genetika. 1986 Mar;22(3):399-405.
PMID:3456952
Abstract
The data of genetic mapping of the cholera toxin regulatory gene by conjugation mating of Vibrio cholerae eltor donor strain with V. cholerae classica recipients are presented. The close genetic linkage of tox locus to pur-63 is shown. The gene order asp - cys - nal - pur-61 - trp - his - pur-63 - tox - ile of the chromosomal region examined is established.
摘要
本文展示了通过霍乱弧菌埃尔托生物型供体菌株与霍乱弧菌古典生物型受体菌株进行接合交配来对霍乱毒素调节基因进行遗传定位的数据。结果表明，tox基因座与pur-63紧密连锁。确定了所检测染色体区域的基因顺序为asp - cys - nal - pur-61 - trp - his - pur-63 - tox - ile。
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