Miller D H, Hornabrook R W, Dagger J, Fong R
J Neurol Neurosurg Psychiatry. 1986 Jan;49(1):43-6. doi: 10.1136/jnnp.49.1.43.
A recent survey revealed 237 cases of multiple sclerosis in Wellington, New Zealand, giving an overall prevalence of 69 cases per 100,000. Two hundred and thirty-five were European with one Asian and only one Maori, confirming the rarity of the disease in Maoris. HLA A3, B7 and DR2 antigens were more frequent in multiple sclerosis patients compared with European controls. The same antigens were much less common in the Maori population. The results suggest that Maoris have a low susceptibility to multiple sclerosis despite living in a high risk area, and that genetic susceptibility may be related to the HLA system.
最近的一项调查显示，新西兰惠灵顿有237例多发性硬化症病例，总体患病率为每10万人中有69例。其中235例为欧洲人，1例亚洲人，仅1例毛利人，这证实了该疾病在毛利人中很罕见。与欧洲对照组相比，多发性硬化症患者中HLA A3、B7和DR2抗原更为常见。相同的抗原在毛利人群体中则要少见得多。结果表明，尽管生活在高危地区，毛利人对多发性硬化症的易感性较低，而且遗传易感性可能与HLA系统有关。
