de Oliveira Faria Sheilla, Hurwitz Gillian, Kim Jaemin, Liberty Jacqueline, Orchard Kimberly, Liu Geoffrey, Barbera Lisa, Howell Doris
Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo 01246-903, Brazil.
Department of Supportive Care, Princess Margaret Cancer Centre, Toronto, ON M5G 2M9, Canada.
J Clin Med. 2021 Sep 15;10(18):4162. doi: 10.3390/jcm10184162.
The aims of this review were to identify symptoms experienced by head and neck cancer (HNC) patients and their prevalence, as well as to compare symptom coverage identified in HNC specific patient-reported outcome measures (PROMs). Searches of Ovid Medline, Embase, PsychInfo, and CINAHL were conducted to identify studies. The search revealed 4569 unique articles and identified 115 eligible studies. The prevalence of reported symptoms was highly variable among included studies. Variability in sample size, timing of the assessments, and the use of different measures was noted across studies. Content mapping of commonly used PROMs showed variability and poor capture of prevalent symptoms, even though validation studies confirmed satisfactory reliability and validity. This suggests limitations of some of the tools in providing an accurate and comprehensive picture of the patient's symptoms and problems.
本综述的目的是确定头颈癌（HNC）患者所经历的症状及其患病率，并比较HNC特定患者报告结局量表（PROMs）中所确定的症状覆盖范围。我们检索了Ovid Medline、Embase、PsychInfo和CINAHL以识别相关研究。检索共发现4569篇独特文章，并确定了115项符合条件的研究。纳入研究中报告症状的患病率差异很大。各研究在样本量、评估时间以及不同测量方法的使用方面存在差异。常用PROMs的内容映射显示存在变异性，且对常见症状的捕捉不佳，尽管验证研究证实其具有令人满意的信度和效度。这表明某些工具在准确全面呈现患者症状和问题方面存在局限性。
