Janiri Delfina, Moccia Lorenzo, Conte Eliana, Palumbo Laura, Chieffo Daniela Pia Rosaria, Fredda Giulia, Menichincheri Renato Maria, Balbi Andrea, Kotzalidis Georgios D, Sani Gabriele, Janiri Luigi
Department of Neuroscience, Section of Psychiatry, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Department of Human Neuroscience, Sapienza University of Rome, 00185 Rome, Italy.
J Pers Med. 2021 Aug 30;11(9):865. doi: 10.3390/jpm11090865.
: Psychopathological dimensions contributing to suicidal ideation in young age are poorly understood. We aimed to investigate the involvement of emotional dysregulation and temperament in suicide risk in a sample of accurately selected young patients with mood disorders and a matched sample of healthy controls (HC). : We assessed 50 young patients (aged 14-25 years) with DSM-5 bipolar or depressive disorders for clinical and psychopathological characteristics and 82 age and sex, educational level, and smoking habits-matched HC. Emotional dysregulation and temperament were assessed using the Difficulties in Emotion Regulation Scale (DERS) and the Temperament Evaluation of Memphis, Pisa, Paris and San Diego-Autoquestionnaire (TEMPS-A-39), respectively. We tested their associations with suicidal ideation, using standard univariate/bivariate methods, preceded by overall multivariate analysis. : In the group of patients, 24 (48%) reported lifetime suicide ideation (LSI). Patients with LSI scored higher on emotional dysregulation ( < 0.001) and cyclothymic ( < 0.001), irritable ( = 0.01), and hyperthymic temperaments ( = 0.003) than HC. Patients with LSI specifically presented with more emotional dysregulation ( < 0.001) and cyclothymic temperament ( = 0.001), than patients without LSI (N = 26). : Temperamental features, in particular cyclothymic temperament, and emotion dysregulation may represent independent factors for increased vulnerability to lifetime suicidal ideation in young adults with mood disorders.
人们对导致年轻人自杀意念的精神病理学维度了解甚少。我们旨在调查情绪调节障碍和气质在准确选择的年轻情绪障碍患者样本以及匹配的健康对照(HC)样本中的自杀风险中的作用。我们评估了50名年龄在14 - 25岁之间、患有DSM - 5双相或抑郁障碍的年轻患者的临床和精神病理学特征,以及82名年龄、性别、教育水平和吸烟习惯相匹配的HC。分别使用情绪调节困难量表(DERS)和孟菲斯、比萨、巴黎和圣地亚哥气质评估 - 自陈问卷(TEMPS - A - 39)评估情绪调节障碍和气质。在进行总体多变量分析之前,我们使用标准单变量/双变量方法测试了它们与自杀意念的关联。在患者组中,24名(48%)报告有终生自杀意念(LSI)。有LSI的患者在情绪调节障碍(<0.001)、环性心境气质(<0.001)、易怒气质(=0.01)和情感高涨气质(=0.003)方面的得分高于HC。与没有LSI的患者(N = 26)相比,有LSI的患者具体表现出更多的情绪调节障碍(<0.001)和环性心境气质(=0.001)。气质特征,特别是环性心境气质和情绪调节障碍,可能是患有情绪障碍的年轻成年人终生自杀意念易感性增加的独立因素。