Department of Electronics and Informatics, Vrije Universiteit Brussel, 1050 Brussels, Belgium.
First Department of Anaesthesiology and Intensive Therapy, Medical University of Lublin, 20-059 Lublin, Poland.
Sensors (Basel). 2021 Sep 7;21(18):5999. doi: 10.3390/s21185999.
Intra-abdominal hypertension, defined as an intra-abdominal pressure (IAP) equal to or above 12 mmHg is one of the major risk-factors for increased morbidity (organ failure) and mortality in critically ill patients. Therefore, IAP monitoring is highly recommended in intensive care unit (ICU) patients to predict development of abdominal compartment syndrome and to provide a better care for patients hospitalized in the ICU. The IAP measurement through the bladder is the actual reference standard advocated by the abdominal compartment society; however, this measurement technique is cumbersome, non-continuous, and carries a potential risk for urinary tract infections and urethral injury. Using microwave reflectometry has been proposed as one of the most promising IAP measurement alternatives. In this study, a novel radar-based method known as transient radar method (TRM) has been used to monitor the IAP in an in vitro model with an advanced abdominal wall phantom. In the second part of the study, further regression analyses have been done to calibrate the TRM system and measure the absolute value of IAP. A correlation of -0.97 with a -value of 0.0001 was found between the IAP and the reflection response of the abdominal wall phantom. Additionally, a quadratic relation with a bias of -0.06 mmHg was found between IAP obtained from the TRM technique and the IAP values recorded by a pressure gauge. This study showed a promising future for further developing the TRM technique to use it in clinical monitoring.
腹内高压，定义为腹腔内压力（IAP）等于或高于 12mmHg，是危重病患者发病率（器官衰竭）和死亡率增加的主要危险因素之一。因此，强烈建议在重症监护病房（ICU）患者中进行 IAP 监测，以预测腹腔间隔室综合征的发展，并为 ICU 住院患者提供更好的护理。通过膀胱进行 IAP 测量是腹腔间隔室协会提倡的实际参考标准；然而，这种测量技术繁琐、不连续，并存在尿路感染和尿道损伤的潜在风险。微波反射测量法已被提出作为最有前途的 IAP 测量替代方法之一。在这项研究中，一种新的基于雷达的方法，即瞬态雷达方法（TRM），已被用于使用先进的腹壁模拟体在体外模型中监测 IAP。在研究的第二部分，进一步进行了回归分析，以校准 TRM 系统并测量 IAP 的绝对值。发现 IAP 与腹壁模拟体的反射响应之间存在 -0.97 的相关性，a 值为 0.0001。此外，还发现 TRM 技术获得的 IAP 与压力计记录的 IAP 值之间存在 -0.06mmHg 的二次关系。这项研究表明，进一步开发 TRM 技术以将其用于临床监测具有广阔的前景。
