Sachs J A, Awad J, McCloskey D, Navarrete C, Festenstein H, Elliot E, Walker-Smith J A, Griffiths C E, Leonard J N, Fry L
Gut. 1986 May;27(5):515-20. doi: 10.1136/gut.27.5.515.
Forty two white patients of British or Irish descent with coeliac disease and 28 with dermatitis herpetiformis were typed for class I HLA-A, B, and C, and class II DR and DQ antigens. In coeliac disease there was a significant increase in the frequencies of A1, B8, DR3, DR7, and DQw2 compared with controls but no increase of DR2. In dermatitis herpetiformis there were similarly increased frequencies of A1, B8, DR3, and DQw2. In contrast with coeliac disease, however, the frequency of DR7 (18%) was no different from the control group but there was an increased frequency of DR2.
对42名患有乳糜泻的英裔或爱尔兰裔白人患者以及28名患有疱疹样皮炎的患者进行了I类HLA - A、B、C以及II类DR和DQ抗原分型。与对照组相比，乳糜泻患者中A1、B8、DR3、DR7和DQw2的频率显著增加，但DR2频率未增加。疱疹样皮炎患者中A1、B8、DR3和DQw2的频率同样增加。然而，与乳糜泻不同的是，DR7的频率（18%）与对照组无差异，但DR2的频率增加。
