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用于生物医学应用的离子液体基材料。

Ionic Liquid-Based Materials for Biomedical Applications.

作者信息

Correia Daniela Maria, Fernandes Liliana Correia, Fernandes Margarida Macedo, Hermenegildo Bruno, Meira Rafaela Marques, Ribeiro Clarisse, Ribeiro Sylvie, Reguera Javier, Lanceros-Méndez Senentxu

机构信息

Centre of Physics, University of Minho, 4710-058 Braga, Portugal.

Centre of Chemistry, University of Trás-os-Montes e Alto Douro, 5000-801 Vila Real, Portugal.

出版信息

Nanomaterials (Basel). 2021 Sep 15;11(9):2401. doi: 10.3390/nano11092401.

Abstract

Ionic liquids (ILs) have been extensively explored and implemented in different areas, ranging from sensors and actuators to the biomedical field. The increasing attention devoted to ILs centers on their unique properties and possible combination of different cations and anions, allowing the development of materials with specific functionalities and requirements for applications. Particularly for biomedical applications, ILs have been used for biomaterials preparation, improving dissolution and processability, and have been combined with natural and synthetic polymer matrixes to develop IL-polymer hybrid materials to be employed in different fields of the biomedical area. This review focus on recent advances concerning the role of ILs in the development of biomaterials and their combination with natural and synthetic polymers for different biomedical areas, including drug delivery, cancer therapy, tissue engineering, antimicrobial and antifungal agents, and biosensing.

摘要

离子液体(ILs)已在不同领域得到广泛研究和应用,从传感器、致动器到生物医学领域。对离子液体日益增加的关注集中在其独特的性质以及不同阳离子和阴离子的可能组合上,这使得能够开发出具有特定功能和应用要求的材料。特别是在生物医学应用中,离子液体已用于生物材料制备、改善溶解性和加工性能,并与天然和合成聚合物基质相结合,以开发用于生物医学领域不同方面的离子液体-聚合物杂化材料。本综述聚焦于离子液体在生物材料开发中的作用以及它们与天然和合成聚合物在不同生物医学领域(包括药物递送、癌症治疗、组织工程、抗菌和抗真菌剂以及生物传感)的结合方面的最新进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d71f/8471968/2bfe0eb7d5e9/nanomaterials-11-02401-g001.jpg

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