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用印尼当地糙米品种替代对2型糖尿病患者人体测量指标及血糖水平改善的影响:一项试点项目

Substitution of local Indonesian varieties of brown rice on anthropometry and blood glucose level improvement in type 2 DM patients: a pilot project.

作者信息

Handayani Dian, Kusumastuty Inggita, Innayah Alma Maghfirotun, Retnaningtyas Ekowati, Sulistyowati Etik, Sasiarini Laksmi, Rudijanto Achmad

机构信息

Department of Nutrition Science, Faculty of Medicine, Universitas Brawijaya, Malang.

Master Program in Biomedical Sciences, Faculty of Medicine, Universitas Brawijaya, Malang.

出版信息

J Public Health Res. 2021 Sep 27;11(1):2283. doi: 10.4081/jphr.2021.2283.

DOI:10.4081/jphr.2021.2283
PMID:34579520
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8859717/
Abstract

BACKGROUND

Diabetes mellitus is a metabolic disorder whose prevalence increases globally. Medical nutrition therapy (MNT) is one of the DM management pillars to control blood glucose. Local Indonesian brown rice is proven to contain high fiber and magnesium levels thus could improve obesity, fasting blood glucose, and HbA1c This study aims to prove the benefits of brown rice on anthropometric parameters and blood glucose control.

DESIGN AND METHODS

Respondents were overweight women older than 40 years with type 2 diabetes who were given three main meals and three snacks six days a week for 12 weeks. Anthropometric and blood glucose control data were collected before and after the intervention. Diet and intake data before the intervention were obtained through a semi quantitate food frequency questionnaire. Intake data during the intervention were recorded using the 24-hour food record and analyzed using modified NutriSurvey 2007 software.

RESULTS

Brown rice intervention significantly reduced body weight, BMI, body fat percentage, and abdominal circumference (p<0.05), also in fasting blood glucose (FBG), 2-h postprandial blood glucose (PBG), and HbA1c (p<0.05). From the Pearson's test results, an increase in fiber intake correlated with a decrease in BMI and abdominal circumference (p=0.03; r = -0.511 and p=0.006; r = -0.619, respectively). Meanwhile, magnesium intake and changes in BMI showed a negative correlation.

CONCLUSIONS

The substitution of brown rice as a staple food for 12 weeks improves anthropometric parameters and blood glucose control in respondents with type 2 diabetes.

摘要

背景

糖尿病是一种代谢紊乱疾病,其全球患病率呈上升趋势。医学营养治疗(MNT)是控制血糖的糖尿病管理支柱之一。事实证明,印度尼西亚当地糙米含有高纤维和镁,因此可以改善肥胖、空腹血糖和糖化血红蛋白。本研究旨在证明糙米对人体测量参数和血糖控制的益处。

设计与方法

研究对象为年龄超过40岁的超重2型糖尿病女性,每周六天提供三餐和三次零食,为期12周。在干预前后收集人体测量和血糖控制数据。干预前的饮食和摄入量数据通过半定量食物频率问卷获得。干预期间的摄入量数据使用24小时食物记录进行记录,并使用改良的2007年营养调查软件进行分析。

结果

糙米干预显著降低了体重、BMI、体脂百分比和腹围(p<0.05),空腹血糖(FBG)、餐后2小时血糖(PBG)和糖化血红蛋白(HbA1c)也显著降低(p<0.05)。根据皮尔逊检验结果,纤维摄入量的增加与BMI和腹围的降低相关(p=0.03;r = -0.511和p=0.006;r = -0.619)。同时,镁摄入量与BMI变化呈负相关。

结论

用糙米替代主食12周可改善2型糖尿病患者的人体测量参数和血糖控制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/205a/8859717/ccc80d87b7c3/jphr-11-1-2283-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/205a/8859717/ad0eb2a3a9ea/jphr-11-1-2283-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/205a/8859717/ccc80d87b7c3/jphr-11-1-2283-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/205a/8859717/ad0eb2a3a9ea/jphr-11-1-2283-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/205a/8859717/ccc80d87b7c3/jphr-11-1-2283-g002.jpg

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Br J Nutr. 2019 Jun;121(12):1389-1397. doi: 10.1017/S000711451900076X. Epub 2019 Apr 22.
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Int J Mol Sci. 2019 Mar 18;20(6):1351. doi: 10.3390/ijms20061351.
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Higher dietary magnesium intake is associated with lower body mass index, waist circumference and serum glucose in Mexican adults.
较高的膳食镁摄入量与墨西哥成年人较低的体重指数、腰围和血清葡萄糖水平有关。
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