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高剂量维生素B6对自闭症儿童的影响：一项双盲交叉研究。

The effect of high doses of vitamin B6 on autistic children: a double-blind crossover study.

作者信息

Rimland B, Callaway E, Dreyfus P

出版信息

Am J Psychiatry. 1978 Apr;135(4):472-5. doi: 10.1176/ajp.135.4.472.

DOI:10.1176/ajp.135.4.472
PMID:345827
Abstract

The authors used data from an earlier nonblind study to identify 16 autistic-type child outpatients who had apparently improved when given vitamin B6 (pyridoxine). In a double-blind study each child's B6 supplement was replaced during two separate experimental trial periods with either a B6 supplement or a matched placebo. Behavior was rated as deteriorating significantly during the B6 withdrawal.

摘要

作者使用早期一项非盲法研究的数据，确定了16名自闭症谱系儿童门诊患者，这些儿童在服用维生素B6（吡哆醇）后症状明显改善。在一项双盲研究中，在两个独立的试验期内，每个孩子的B6补充剂被换成B6补充剂或匹配的安慰剂。在停用B6期间，行为评分显著恶化。

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The effect of high doses of vitamin B6 on autistic children: a double-blind crossover study.高剂量维生素B6对自闭症儿童的影响：一项双盲交叉研究。
Am J Psychiatry. 1978 Apr;135(4):472-5. doi: 10.1176/ajp.135.4.472.
2
Clinical and biological effects of high doses of vitamin B6 and magnesium on autistic children.高剂量维生素B6和镁对自闭症儿童的临床及生物学效应
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Effects of pyridoxine and magnesium on autistic symptoms--initial observations.维生素B6和镁对自闭症症状的影响——初步观察
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Vitamin B6, magnesium, and combined B6-Mg: therapeutic effects in childhood autism.维生素B6、镁以及维生素B6与镁的联合应用：对儿童自闭症的治疗效果
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[Clinical and biochemical value of Magnesium + vitamin B6 combination in the treatment of residual autism in adults].
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[Value of behavior scales and urinary homovanillic acid determinations in monitoring the combined treatment with vitamin B6 and magnesium of children displaying autistic behavior].[行为量表及尿高香草酸测定在监测维生素B6与镁联合治疗自闭症行为儿童中的价值]
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