Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, 315201, China; University of Chinese Academy of Sciences 19 A Yuquan Rd, Shijingshan District, Beijing 100049, China.
Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo, 315201, China.
J Colloid Interface Sci. 2022 Feb;607(Pt 2):1424-1435. doi: 10.1016/j.jcis.2021.09.052. Epub 2021 Sep 17.
Material that resists biofouling adhesion is needed in a complex marine environment, but few of them can combine ultra-low fouling and environmental friendliness. Slippery lubricant-infused porous surface (SLIPS) is such a material, but it lacks the contact-killing ability, which limits its stability and anti-fouling efficiency. Here, we report a metal organic framework (MOF-based) Slippery ionic liquid-infused surface with excellent antifouling performance via synergistic release and contact-killing defense strategy. The dense needle-like MIL-110 array, grown in situ on the aluminum surface, is conducive to the stable storage of quaternary ammonium salt (QAS) ionic liquid. Compared to the control group with mature biofilm formed on the surface, SLIPS showed non-fouling performance in a 10-day test and another 21-day test under more challenging conditions. The adsorption amount of lipopolysaccharide (LPS) on SLIPS was 50% lower than that on the aluminum sheet and the aluminum sheet with MIL-110 grown on the surface as the control groups within three hours. The relationship between bacterial adhesion and LPS adsorption indicated that the anti-adhesion performance of SLIPS was mediated by the weak adhesion and easy release property of its surface to extracellular fouling molecules. This study provides the possibility to systematically reveal the antifouling mechanism of SLIPS on bacterial adhesion.
在复杂的海洋环境中需要具有抗生物附着性能的材料，但很少有材料能兼具超低附着性和环境友好性。滑润剂注入多孔表面（SLIPS）就是这样一种材料，但它缺乏接触杀灭能力，这限制了其稳定性和抗污效率。在这里，我们通过协同释放和接触杀灭防御策略，报道了一种具有优异抗污性能的基于金属有机骨架（MOF 基）滑润离子液体注入表面。密集的针状 MIL-110 阵列原位生长在铝表面上，有利于季铵盐（QAS）离子液体的稳定储存。与表面形成成熟生物膜的对照组相比，SLIPS 在 10 天测试和更具挑战性条件下的另一个 21 天测试中表现出非附着性能。在三个小时内，SLIPS 对脂多糖（LPS）的吸附量比铝片和作为对照组的表面生长 MIL-110 的铝板低 50%。细菌附着与 LPS 吸附之间的关系表明，SLIPS 的抗附着性能是由其表面对细胞外污垢分子的弱附着和易于释放特性介导的。本研究为系统揭示 SLIPS 对细菌附着的抗污机制提供了可能性。
