Burke J R, Cowley D M, Mottram B M, Buckner P
Aust N Z J Med. 1986 Feb;16(1):43-7. doi: 10.1111/j.1445-5994.1986.tb01114.x.
A calcium loading test performed on seven of eight children with idiopathic hypercalciuria identified the hyperabsorptive form of hypercalciuria in five and renal hypercalciuria in one. The type of hypercalciuria was not identified in the other patient. Three children presented with hematuria without calculus formation. Chlorothiazide reduced the urinary calcium excretion level in two of six patients to the normal range. The addition of cellulose phosphate to chlorothiazide reduced the urinary calcium excretion level to the normal range in those four patients who showed an incomplete response to chlorothiazide alone. There was clinical improvement with cellulose phosphate in another child whose symptoms did not disappear after chlorothiazide had reduced urinary calcium level to the normal range. Cellulose phosphate is effective in children with recurrent stone formation who have shown inadequate response to chlorothiazide.
对8名特发性高钙尿症患儿中的7名进行了钙负荷试验，结果发现其中5名患儿为高吸收型高钙尿症，1名患儿为肾性高钙尿症。另1名患儿的高钙尿症类型未明确。3名患儿出现血尿但未形成结石。氯噻嗪使6名患者中的2名尿钙排泄水平降至正常范围。在氯噻嗪治疗效果不完全的4名患者中，加用磷酸纤维素后尿钙排泄水平降至正常范围。另一名患儿在氯噻嗪将尿钙水平降至正常范围后症状仍未消失，使用磷酸纤维素后临床症状有所改善。磷酸纤维素对氯噻嗪治疗反应不佳的复发性结石形成患儿有效。
