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支气管镜相关. 的比较基因组分析与表型特征描述

Comparative Genomic Analysis and Phenotypic Characterization of Bronchoscope-Associated .

机构信息

Disinfection and Sterilization Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

Department of Laboratory Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

出版信息

Pol J Microbiol. 2021 Sep;70(3):409-412. doi: 10.33073/pjm-2021-038. Epub 2021 Sep 17.

DOI:10.33073/pjm-2021-038
PMID:34584536
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8459003/
Abstract

Bronchoscopes have been linked to outbreaks of nosocomial infections. The phenotypic and genomic profiles of bronchoscope-associated isolates are largely unknown. In this work, a total of 358 isolates and 13 isolates were recovered from samples after clinical procedures and samples after decontamination procedures, respectively, over the five months. Antimicrobial susceptibility testing found seven isolates exhibiting a low-level resistance to antimicrobial agents. Among seven isolates, we found five sequence types (STs) clustered into three main clades. Collectively, this study described for the first time the phenotypic and genomic characteristics of bronchoscope-associated .

摘要

支气管镜已被证实与医院感染的爆发有关。目前,人们对与支气管镜相关的分离株的表型和基因组特征知之甚少。在这项研究中,我们在五个月内,分别从临床操作后样本和消毒后样本中,共回收了 358 株和 13 株分离株。药敏试验发现,有 7 株分离株对一种或多种抗菌药物表现出低水平耐药性。在这 7 株分离株中,我们发现有 5 种序列类型(STs)聚集成 3 个主要分支。总的来说,这项研究首次描述了与支气管镜相关的分离株的表型和基因组特征。

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mSystems. 2020 Jun 23;5(3):e00498-20. doi: 10.1128/mSystems.00498-20.
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Analysis of an improved workflow of endoscope reprocessing for bedside endoscopic diagnosis and treatment on COVID-19 patients.分析一种改进的 COVID-19 患者床边内镜诊断和治疗用内镜再处理工作流程。
J Zhejiang Univ Sci B. 2020 May;21(5):416-422. doi: 10.1631/jzus.B2000109. Epub 2020 May 9.
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New insights into the mechanisms of colistin resistance in Klebsiella aerogenes of clinical origin.
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Int J Antimicrob Agents. 2020 Jun;55(6):105990. doi: 10.1016/j.ijantimicag.2020.105990. Epub 2020 Apr 21.
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Carbapenem-Resistant Clinical Isolates from a Teaching Hospital in Southwestern China: Detailed Molecular Epidemiology, Resistance Determinants, Risk Factors and Clinical Outcomes.来自中国西南部一家教学医院的耐碳青霉烯临床分离株:详细的分子流行病学、耐药决定因素、危险因素及临床结局
Infect Drug Resist. 2020 Feb 19;13:577-585. doi: 10.2147/IDR.S235975. eCollection 2020.
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