Center of Endoscopy, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.
Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310003, China.
J Zhejiang Univ Sci B. 2020 May;21(5):416-422. doi: 10.1631/jzus.B2000109. Epub 2020 May 9.
Severe cases infected with the coronavirus disease 2019 (COVID-19), named by the World Health Organization (WHO) on Feb. 11, 2020, tend to present a hypercatabolic state because of severe systemic consumption, and are susceptible to stress ulcers and even life-threatening gastrointestinal bleeding. Endoscopic diagnosis and treatment constitute an irreplaceable part in the handling of severe COVID-19 cases. Endoscopes, as reusable precision instruments with complicated structures, require more techniques than other medical devices in cleaning, disinfection, sterilization, and other reprocessing procedures. From 2016 to 2019, health care-acquired infection caused by improper endoscope reprocessing has always been among the top 5 on the list of top 10 health technology hazards issued by the Emergency Care Research Institute. Considering the highly infective nature of COVID-19 and the potential aerosol contamination therefrom, it is of pivotal significance to ensure that endoscopes are strictly reprocessed between uses. In accordance with the national standard "Regulation for Cleaning and Disinfection Technique of Flexible Endoscope (WS507-2016)," we improved the workflow of endoscope reprocessing including the selection of chemicals in an effort to ensure quality control throughout the clinical management towards COVID-19 patients. Based on the experience we attained from the 12 severe COVID-19 cases in our hospital who underwent endoscopy 23 times in total, the article provides an improved version of endoscopic reprocessing guidelines for bedside endoscopic diagnosis and treatment on COVID-19 patients for reference.
2020 年 2 月 11 日,世界卫生组织(WHO)将这种疾病命名为 2019 冠状病毒病(COVID-19)。严重感染 2019 冠状病毒病的病例往往会出现高代谢状态,这是由于全身严重消耗所致,易发生应激性溃疡,甚至有生命威胁的胃肠道出血。内镜诊断和治疗是处理严重 COVID-19 病例不可或缺的一部分。内镜作为结构复杂的重复使用精密仪器,在清洗、消毒、灭菌等再处理程序中比其他医疗器械需要更多的技术。从 2016 年到 2019 年,由于内镜处理不当而导致的医源性感染一直是急诊研究所在发布的十大卫生技术危害清单中排名前 5 的原因之一。考虑到 COVID-19 的高度传染性以及由此产生的潜在气溶胶污染,确保在使用之间对内镜进行严格的再处理至关重要。我们根据国家标准《软式内镜清洗消毒技术规范(WS507-2016)》,改进了内镜再处理的工作流程,包括化学物质的选择,努力确保在对 COVID-19 患者进行临床管理的全过程中进行质量控制。基于我们从本院 12 例总共接受了 23 次内镜检查的严重 COVID-19 病例中获得的经验,本文为床边内镜诊断和治疗 COVID-19 患者提供了经改进的内镜再处理指南,供参考。