全口义齿对无牙颌患者长期口腔健康相关生活质量的影响：一项系统评价与Meta分析

The effect of complete dentures on edentulous patients' oral health-related quality of life in long-term: A systematic review and meta-analysis.

作者信息

Martins Angela M C, Guimarães Ludmila S, Campos Camila H, Küchler Erika C, Pereira Daniele M S, Maia Lucianne C, Antunes Leonardo S, Antunes Lívia A A

机构信息

Postgraduate Program in Dentistry, School of Dentistry, Fluminense Federal University, Niterói, Brazil.

Department of Specific Formation, School of Dentistry, Fluminense Federal University, Nova Friburgo, Brazil.

出版信息

Dent Res J (Isfahan). 2021 Aug 18;18:65. eCollection 2021.

PMID:34584643

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8428284/

Abstract

BACKGROUND

To evaluate whether the long-term use of complete dentures (CD) into promotes significant changes in the oral health-related quality of life (OHRQoL) in edentulous patients.

METHODS

A systematic review and meta-analysis was conducted. A broad search in Pubmed, Web of Science, Scopus, Cochrane Library, Grey Literature, clinical trials registers and manual search was done. The eligibility criteria were based on population, intervention, comparisons and outcome: (P) edentulous patients, (I) CDs rehabilitation, (C) OHRQoL after CD, (O) change in scores of OHRQoL. Two independent reviewers applied the eligibility criteria, collected qualitative data, performed methodological quality and evaluated the certainty of the evidence (grading of recommendations assessment, development and evaluation). The meta-analysis was analyzed in RevMan 5.4 with 95% confidence intervals (CIs) and < 0.05.

RESULTS

A total of 2452 records were identified. Twenty-four articles were included in qualitative synthesis. Nineteen studies were qualified as good, 3 as fair and 2 as poor quality. Twelve studies were included in quantitative analysis (meta-analysis). The use of CD did not improved OHRQoL in a period of 3 months through the assessment of the Geriatric Oral Health Assessment Index (GOHAI) instrument ( = 0.55; CI; 6.86 [-15.60, 29.31]), and Oral Health Impact Profile-14 (OHIP-14) ( = 0.05; CI; -14.91 [-29.87, 0.04]), with very low certainty of evidence. In a long term, 6 months, GOHAI instrument ( < 0.00001; CI; 16.22 [10.70, 21.74]), OHIP 20 ( = 0.02; CI; -11.09 [-20.54, -1.64]) and OHIP-EDENT ( = 0.0004; CI; -8.59 [-13.32, -3.86]) showed improvement on OHRQoL, with very low and low evidence of certainty, respectively.

CONCLUSION

CD has the strong potential to contribute to oral health-related quality of life in long-term.

摘要

背景

评估长期佩戴全口义齿（CD）是否能促进无牙颌患者口腔健康相关生活质量（OHRQoL）的显著变化。

方法

进行了一项系统评价和荟萃分析。在PubMed、科学网、Scopus、Cochrane图书馆、灰色文献、临床试验注册库中进行了广泛检索，并进行了手工检索。纳入标准基于人群、干预措施、对照和结局：（P）无牙颌患者，（I）全口义齿修复，（C）佩戴全口义齿后的OHRQoL，（O）OHRQoL评分变化。两名独立评审员应用纳入标准，收集定性数据，评估方法学质量并评估证据的确定性（推荐评估、制定和评价分级）。在RevMan 5.4中进行荟萃分析，置信区间为95%，P<0.05。

结果

共识别出2452条记录。24篇文章纳入定性综合分析。19项研究质量为良好，3项为中等，2项为较差。12项研究纳入定量分析（荟萃分析）。通过老年口腔健康评估指数（GOHAI）工具评估，在3个月内佩戴全口义齿并未改善OHRQoL（平均差=0.55；可信区间；6.86[-15.60,29.31]），以及口腔健康影响程度量表-14（OHIP-14）（平均差=0.05；可信区间；-14.91[-29.87,0.04]），证据确定性极低。从长期来看，6个月时，GOHAI工具（P<0.00001；可信区间；16.22[10.70,21.74]）、OHIP 20（平均差=0.02；可信区间；-11.09[-20.54,-1.64]）和OHIP-EDENT（平均差=0.0004；可信区间；-8.59[-13.32,-3.86]）显示OHRQoL有所改善，证据确定性分别为极低和低。