Division of Ophthalmology, Surgical Specialties and Anesthesiology Department, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista "Júlio de Mesquita Filho", Botucatu, SP, Brazil.
Arq Bras Oftalmol. 2022 May-Jun;85(3):249-254. doi: 10.5935/0004-2749.20220036.
Creating models, in pediatric cataracts, to estimate kerotometry and axial length values at future ages, based on kerotometry and axial length measured at surgery, to estimate the intraocular lens power for emmetropia in future ages.
Eyes with bilateral cataract and kerotometry and axial length measured at surgery and at least one postoperative examination with kerotometry and axial length measurements, were considered for this study. The models to estimate future kerotometry and axial length values were created considering (1) kerotometry and axial length measured at surgery, (2) the average slope of kerotometry and axial length logarithmic regression created for every single eye and (3) age at surgery. The intraocular lens for future ages can be estimated using these values in third generation formulas. The estimation errors for kerotometry, axial length and intraocular lens were also calculated.
A total of 57 eyes from 29 patients met the inclusion criteria. The average age at the surgery and follow-up was 36.96 ± 32.04 months and 2.39 ± 1.46 years, respectively. The average slope of logarithmic regression created for every single eye were -3.286 for kerotometry and +3.189 for axial length. The average absolute estimation errors for kerotometry and axial length were respectively: 0.61 ± 0.54 D and 0.49 ± 0.55 mm, and for intraocular lens using SRK-T, Hoffer-Q and Holladay I formulas were: 2 . 04 ± 1 . 73 D , 2 . 49 ± 2 . 10 D and 2 . 26 ± 1 . 87 D , respectively.
The presented models could be used to estimate the intraocular lens power for emmetropia at future ages to guide the choice of the intraocular lens power to be implanted in pediatric cataract.
建立模型，以根据手术时测量的角膜曲率和眼轴长度来预测未来年龄的角膜曲率和眼轴长度值，从而预测未来年龄的近视患者的人工晶状体度数。
本研究纳入了双眼白内障且手术时测量了角膜曲率和眼轴长度，且术后至少有一次角膜曲率和眼轴长度测量的患者。用于预测未来角膜曲率和眼轴长度值的模型考虑了以下因素：（1）手术时测量的角膜曲率和眼轴长度，（2）为每只眼创建的角膜曲率和眼轴长度对数回归的平均斜率，（3）手术时的年龄。可以使用这些值在第三代公式中估算未来年龄的人工晶状体。还计算了角膜曲率、眼轴长度和人工晶状体的估计误差。
共有 29 名患者的 57 只眼符合纳入标准。手术和随访时的平均年龄分别为 36.96±32.04 个月和 2.39±1.46 年。为每只眼创建的对数回归的平均斜率分别为角膜曲率的-3.286 和眼轴长度的+3.189。角膜曲率和眼轴长度的平均绝对估计误差分别为：0.61±0.54 D 和 0.49±0.55 mm，使用 SRK-T、Hoffer-Q 和 Holladay I 公式计算的人工晶状体的平均绝对估计误差分别为：2.04±1.73 D、2.49±2.10 D 和 2.26±1.87 D。
本研究提出的模型可用于预测未来年龄的近视患者的人工晶状体度数，以指导儿童白内障患者人工晶状体度数的选择。
