University of California-Davis, School of Veterinary Medicine, Davis, California, USA.
Ohio State University, College of Veterinary Medicine, Columbus, Ohio, USA.
J Vet Intern Med. 2021 Nov;35(6):2722-2729. doi: 10.1111/jvim.16176. Epub 2021 Sep 29.
Limited information currently exists regarding the clinical progression and outcomes of cats that undergo choledochal stenting as a treatment for extrahepatic biliary obstruction (EHBO).
HYPOTHESIS/OBJECTIVES: Describe clinical characteristics, indications for choledochal stent placement, procedure, and outcomes in a cohort of cats undergoing choledochal stenting and evaluate risk factors associated with survival as well as recurrence of EHBO in affected cats.
Twenty-three client-owned cats undergoing choledochal stent placement.
Retrospective study. Medical records from 6 academic institutions were reviewed, and data were extracted and analyzed statistically.
Median age of cats was 10.1 years (range, 2-16), and all cats had at least 2 clinical signs. Most common clinical signs were vomiting in 20/22 (90.9%), inappetence in 19/22 (86.4%), and lethargy in 19/23 (82.6%). Procedural complications were uncommon and rarely related to the stenting procedure. Clinical signs improved postoperatively in 15/20 (75.0%) cats and serum total bilirubin concentration decreased postoperatively in 13/19 (68.4%) cats. Eighteen (78.3%) cats survived to discharge. Recurrence of EHBO was documented in 7/18 (38.9%) cats that survived to discharge. Cholelithiasis was associated with recurrence of EHBO. Median survival time for cats that survived to discharge was 931 days (range, 19-3034). Absence of peritoneal effusion was associated with survival to discharge.
Choledochal stenting was an effective treatment modality in cats with EHBO with few procedural complications and potential for prolonged survival, but substantial risk for recurrence of EHBO was identified.
目前关于接受胆总管支架置入术治疗肝外胆管阻塞(EHBO)的猫的临床进展和结果的信息有限。
假设/目的:描述接受胆总管支架置入术的猫的临床特征、胆总管支架置入的适应证、手术过程和结果,并评估与受影响猫的生存和 EHBO 复发相关的风险因素。
23 只接受胆总管支架置入术的患宠猫。
回顾性研究。分析 6 家学术机构的病历记录,并提取和统计数据。
猫的中位年龄为 10.1 岁(范围,2-16 岁),所有猫均至少有 2 种临床症状。最常见的临床症状为 20/22(90.9%)猫呕吐、19/22(86.4%)猫食欲不振和 19/23(82.6%)猫嗜睡。手术并发症不常见,且很少与支架置入术有关。15/20(75.0%)的猫术后临床症状改善,13/19(68.4%)的猫术后血清总胆红素浓度降低。18 只(78.3%)猫存活至出院。18 只存活至出院的猫中有 7 只(38.9%)发生 EHBO 复发。胆石症与 EHBO 复发有关。存活至出院的猫的中位生存时间为 931 天(范围,19-3034 天)。无腹腔积液与存活至出院有关。
胆总管支架置入术是治疗 EHBO 猫的有效方法,手术并发症少,生存时间可能延长,但 EHBO 复发的风险较大。