Tsai C C, Taichman N S
J Clin Periodontol. 1986 Apr;13(4):330-1. doi: 10.1111/j.1600-051x.1986.tb02231.x.
Juvenile periodontitis is associated with a high incidence of infection by Actinobacillus actinomycetemcomitans (Aa). The data presented indicate that the ability of Aa to destroy human PMNs is altered during the course of infection. Leukotoxic strains of Aa are characteristically found in isolates obtained from younger patients (6-12 years of age) but not in older subjects (13-25 years old). This suggests that the leukotoxin may be more important during early as opposed to more advanced phases of juvenile periodontitis.
青少年牙周炎与伴放线放线杆菌（Aa）感染的高发生率相关。所呈现的数据表明，Aa破坏人类中性粒细胞的能力在感染过程中会发生改变。Aa的白细胞毒素菌株典型地存在于从较年轻患者（6 - 12岁）分离出的菌株中，而在年龄较大的受试者（13 - 25岁）中则不存在。这表明白细胞毒素在青少年牙周炎的早期阶段可能比在更晚期阶段更为重要。
