• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

口服营养补充剂对营养不良或有营养不良风险的社区老年人营养状况的影响。

The effect of oral nutritional supplements on the nutritional status of community elderly people with malnutrition or risk of malnutrition.

机构信息

Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Zhengzhou, China.

Zhoukou center for disease control and prevention, Zhoukou, China.

出版信息

Asia Pac J Clin Nutr. 2021 Sep;30(3):415-423. doi: 10.6133/apjcn.202109_30(3).0008.

DOI:10.6133/apjcn.202109_30(3).0008
PMID:34587701
Abstract

BACKGROUND AND OBJECTIVES

To evaluate the effect of oral nutritional supplements (ONS) on community elderly people with malnutrition or risk of malnutrition.

METHODS AND STUDY DESIGN

A single arm intervention trial for 3 months was conducted. Whole nutrient powder was given to all the participants. Dietary intakes were measured by 3-day diet record. Nutritional status was evaluated using body weight, body mass index (BMI), calf circumference (CC), and Mini Nutritional Assessment Short-Form (MNA-SF) scores. Muscle mass was measured by bioimpedance analysis (BIA). All these parameters as well as muscle strength, physical function, and quality of life were measured at both the baseline and the end.

RESULTS

Compared with the baseline, ONS increased protein intake (58.32±16.67 vs 41.90±18.49 g/d, p<0.001), body weight (57.03±8.31 vs 56.68±8.23 kg, p<0.05), BMI (22.16±2.13 vs 22.02±2.08 kg/m2, p<0.05), CC (34.21±2.53 vs 33.80±2.53 cm, p<0.001), MNA-SF scores (12.61±1.43 vs 10.48±0.99, p<0.05), hand grip strength (24.54±8.05 vs 23.27±7.74 kg, p<0.001), and 6-m gait speed (1.11±0.33 vs 0.96±0.28 m/s, p<0.001). Moreover, SF-36 scores of the overall subjects have been improved in all dimensions (p<0.05).

CONCLUSIONS

The study demonstrated that ONS can effectively increase protein intake and improve nutritional status, muscle strength, physical function and quality of life of the elderly with malnutrition or malnutrition risk in communities.

摘要

背景与目的

评估口服营养补充剂(ONS)对社区中营养不良或存在营养不良风险的老年人的影响。

方法和研究设计

进行了为期 3 个月的单臂干预试验。所有参与者均给予全营养素粉。通过 3 天饮食记录来测量饮食摄入量。使用体重、体重指数(BMI)、小腿围(CC)和迷你营养评估简表(MNA-SF)评分来评估营养状况。使用生物电阻抗分析(BIA)来测量肌肉量。在基线和结束时,均测量所有这些参数以及肌肉力量、身体功能和生活质量。

结果

与基线相比,ONS 增加了蛋白质摄入(58.32±16.67 与 41.90±18.49 g/d,p<0.001)、体重(57.03±8.31 与 56.68±8.23 kg,p<0.05)、BMI(22.16±2.13 与 22.02±2.08 kg/m2,p<0.05)、CC(34.21±2.53 与 33.80±2.53 cm,p<0.001)、MNA-SF 评分(12.61±1.43 与 10.48±0.99,p<0.05)、手握力(24.54±8.05 与 23.27±7.74 kg,p<0.001)和 6 米步行速度(1.11±0.33 与 0.96±0.28 m/s,p<0.001)。此外,所有受试者的 SF-36 评分在各个维度均有所提高(p<0.05)。

结论

该研究表明,ONS 可有效增加蛋白质摄入,改善社区中营养不良或存在营养不良风险的老年人的营养状况、肌肉力量、身体功能和生活质量。

相似文献

1
The effect of oral nutritional supplements on the nutritional status of community elderly people with malnutrition or risk of malnutrition.口服营养补充剂对营养不良或有营养不良风险的社区老年人营养状况的影响。
Asia Pac J Clin Nutr. 2021 Sep;30(3):415-423. doi: 10.6133/apjcn.202109_30(3).0008.
2
A comparative intervention trial of deer milk and an oral nutritional supplement efficacy for improving older adults' nutritional status, muscle mass and physical performance.鹿奶与口服营养补充剂改善老年人营养状况、肌肉量和身体机能的比较干预试验。
Clin Nutr ESPEN. 2023 Oct;57:346-357. doi: 10.1016/j.clnesp.2023.07.018. Epub 2023 Jul 20.
3
Impact of specialized oral nutritional supplement on clinical, nutritional, and functional outcomes: A randomized, placebo-controlled trial in community-dwelling older adults at risk of malnutrition.专门的口服营养补充对临床、营养和功能结局的影响:一项在有营养不良风险的社区居住的老年人中进行的随机、安慰剂对照试验。
Clin Nutr. 2021 Apr;40(4):1879-1892. doi: 10.1016/j.clnu.2020.10.015. Epub 2020 Oct 15.
4
Effect of multicomponent intervention on malnutrition in older adults: A multicenter randomized clinical trial.多组分干预对老年人营养不良的影响:一项多中心随机临床试验。
Clin Nutr ESPEN. 2024 Apr;60:31-40. doi: 10.1016/j.clnesp.2024.01.004. Epub 2024 Jan 11.
5
Comparison of two nutrition assessment tools in surgical elderly inpatients in Northern China.中国北方老年外科住院患者两种营养评估工具的比较
Nutr J. 2015 Jul 14;14:68. doi: 10.1186/s12937-015-0054-8.
6
Effects of a low-volume, nutrient- and energy-dense oral nutritional supplement on nutritional and functional status: a randomized, controlled trial in nursing home residents.低容量、高营养和高能量口服营养补充剂对营养和功能状态的影响:养老院居民的随机对照试验。
J Am Med Dir Assoc. 2013 Aug;14(8):628.e1-8. doi: 10.1016/j.jamda.2013.05.011. Epub 2013 Jun 25.
7
Results of High-Protein, High-Calorie Oral Nutritional Supplementation in Malnourished Older People in Nursing Homes: An Observational, Multicenter, Prospective, Pragmatic Study (PROT-e-GER).养老院营养不良老年人高蛋白、高热量口服营养补充的结果:一项观察性、多中心、前瞻性、实用研究(PROT-e-GER)。
J Am Med Dir Assoc. 2021 Sep;22(9):1919-1926.e5. doi: 10.1016/j.jamda.2021.02.039. Epub 2021 Apr 2.
8
Is It Possible Using Handgrip Strength Instead of Body Mass Index in MNA-SF Test to Assess the Nutritional Status of Geriatric Patients?在MNA-SF测试中,是否可以用握力代替体重指数来评估老年患者的营养状况?
J Nutr Health Aging. 2017;21(5):579-584. doi: 10.1007/s12603-016-0744-8.
9
The impact of an oral nutritional supplement on body weight gain in older adults with malnutrition: an open-label randomized controlled trial.口服营养补充剂对营养不良老年人体重增加的影响:一项开放标签随机对照试验。
Trials. 2023 Oct 2;24(1):625. doi: 10.1186/s13063-023-07622-4.
10
Use of a nutrition-focused quality improvement program for community-living older adults at malnutrition risk is associated with better nutritional outcomes.使用以营养为重点的质量改进计划来改善有营养不良风险的社区居住的老年人的营养状况与更好的营养结果相关。
Clin Nutr ESPEN. 2022 Apr;48:291-297. doi: 10.1016/j.clnesp.2022.01.032. Epub 2022 Feb 2.

引用本文的文献

1
Randomised Trial Shows Readymade Oral Nutritional Supplements in Older Malnourished People in the Community Improve Total Nutrient Intakes and Meet More Dietary Reference Values Without Reducing Intake from the Diet.随机试验表明,社区中营养不良的老年人服用即食型口服营养补充剂可提高总营养素摄入量,并达到更多膳食参考值,同时不会减少从日常饮食中的摄入量。
Nutrients. 2025 Jul 29;17(15):2474. doi: 10.3390/nu17152474.
2
Effects of high-protein nutritional supplementation on nutritional status, physical function, and quality of life in older gastric cancer patients receiving neoadjuvant chemotherapy: a randomized trial.高蛋白营养补充对接受新辅助化疗的老年胃癌患者营养状况、身体功能和生活质量的影响:一项随机试验。
Support Care Cancer. 2025 Aug 9;33(9):775. doi: 10.1007/s00520-025-09822-x.
3
Comparative effects of oral nutritional supplementation vs. nutritional education on appetite and weight in older adults with anorexia of aging: a 12-week non-randomized controlled trial.口服营养补充剂与营养教育对老年厌食症患者食欲和体重的比较效果:一项为期12周的非随机对照试验。
Front Nutr. 2025 May 20;12:1606008. doi: 10.3389/fnut.2025.1606008. eCollection 2025.
4
Effect of oral nutrition supplements on anthropometric and functional parameters among community-dwelling older adults: a systematic review and meta-analysis of randomized controlled trials.口服营养补充剂对社区居住老年人人体测量和功能参数的影响:一项随机对照试验的系统评价和荟萃分析
BMC Nutr. 2025 Feb 13;11(1):42. doi: 10.1186/s40795-025-01010-8.
5
Dietary inflammatory index and disability among older adults in Guangzhou: a cross-sectional analysis.广州老年人的饮食炎症指数与残疾状况:一项横断面分析
Front Public Health. 2025 Jan 22;12:1476095. doi: 10.3389/fpubh.2024.1476095. eCollection 2024.
6
Effect of peanut butter supplementation on physical and cognitive functions in community-dwelling older adults: study protocol for a 6-month randomised controlled trial.花生酱补充对社区老年人身体和认知功能的影响:一项为期 6 个月的随机对照试验研究方案。
BMJ Open. 2024 Sep 5;14(9):e086232. doi: 10.1136/bmjopen-2024-086232.
7
How quality of life is measured in studies of nutritional intervention: a systematic review.营养干预研究中生活质量的测量方法:系统评价。
Health Qual Life Outcomes. 2024 Jan 24;22(1):9. doi: 10.1186/s12955-024-02229-y.
8
Preoperative prognostic nutrition index can independently predict the 6-month prognosis of elderly patients undergoing neurosurgical clipping for aneurysmal subarachnoid hemorrhage.术前预后营养指数可独立预测行神经外科夹闭术的老年动脉瘤性蛛网膜下腔出血患者的 6 个月预后。
Neurosurg Rev. 2023 May 10;46(1):117. doi: 10.1007/s10143-023-02021-4.
9
The Impact of Nutrition-Based Interventions on Nutritional Status and Metabolic Health in Small Island Developing States: A Systematic Review and Narrative Synthesis.基于营养干预对小岛屿发展中国家营养状况和代谢健康影响的系统评价和叙述性综合。
Nutrients. 2022 Aug 26;14(17):3529. doi: 10.3390/nu14173529.