Department of Nutrition and Food Hygiene, College of Public Health, Zhengzhou University, Zhengzhou, China.
Zhoukou center for disease control and prevention, Zhoukou, China.
Asia Pac J Clin Nutr. 2021 Sep;30(3):415-423. doi: 10.6133/apjcn.202109_30(3).0008.
To evaluate the effect of oral nutritional supplements (ONS) on community elderly people with malnutrition or risk of malnutrition.
A single arm intervention trial for 3 months was conducted. Whole nutrient powder was given to all the participants. Dietary intakes were measured by 3-day diet record. Nutritional status was evaluated using body weight, body mass index (BMI), calf circumference (CC), and Mini Nutritional Assessment Short-Form (MNA-SF) scores. Muscle mass was measured by bioimpedance analysis (BIA). All these parameters as well as muscle strength, physical function, and quality of life were measured at both the baseline and the end.
Compared with the baseline, ONS increased protein intake (58.32±16.67 vs 41.90±18.49 g/d, p<0.001), body weight (57.03±8.31 vs 56.68±8.23 kg, p<0.05), BMI (22.16±2.13 vs 22.02±2.08 kg/m2, p<0.05), CC (34.21±2.53 vs 33.80±2.53 cm, p<0.001), MNA-SF scores (12.61±1.43 vs 10.48±0.99, p<0.05), hand grip strength (24.54±8.05 vs 23.27±7.74 kg, p<0.001), and 6-m gait speed (1.11±0.33 vs 0.96±0.28 m/s, p<0.001). Moreover, SF-36 scores of the overall subjects have been improved in all dimensions (p<0.05).
The study demonstrated that ONS can effectively increase protein intake and improve nutritional status, muscle strength, physical function and quality of life of the elderly with malnutrition or malnutrition risk in communities.
评估口服营养补充剂(ONS)对社区中营养不良或存在营养不良风险的老年人的影响。
进行了为期 3 个月的单臂干预试验。所有参与者均给予全营养素粉。通过 3 天饮食记录来测量饮食摄入量。使用体重、体重指数(BMI)、小腿围(CC)和迷你营养评估简表(MNA-SF)评分来评估营养状况。使用生物电阻抗分析(BIA)来测量肌肉量。在基线和结束时,均测量所有这些参数以及肌肉力量、身体功能和生活质量。
与基线相比,ONS 增加了蛋白质摄入(58.32±16.67 与 41.90±18.49 g/d,p<0.001)、体重(57.03±8.31 与 56.68±8.23 kg,p<0.05)、BMI(22.16±2.13 与 22.02±2.08 kg/m2,p<0.05)、CC(34.21±2.53 与 33.80±2.53 cm,p<0.001)、MNA-SF 评分(12.61±1.43 与 10.48±0.99,p<0.05)、手握力(24.54±8.05 与 23.27±7.74 kg,p<0.001)和 6 米步行速度(1.11±0.33 与 0.96±0.28 m/s,p<0.001)。此外,所有受试者的 SF-36 评分在各个维度均有所提高(p<0.05)。
该研究表明,ONS 可有效增加蛋白质摄入,改善社区中营养不良或存在营养不良风险的老年人的营养状况、肌肉力量、身体功能和生活质量。