基因沉默的综合机制及其在植物生长发育中的作用

Comprehensive Mechanism of Gene Silencing and Its Role in Plant Growth and Development.

作者信息

El-Sappah Ahmed H, Yan Kuan, Huang Qiulan, Islam Md Monirul, Li Quanzi, Wang Yu, Khan Muhammad Sarwar, Zhao Xianming, Mir Reyazul Rouf, Li Jia, El-Tarabily Khaled A, Abbas Manzar

机构信息

School of Agriculture, Forestry and Food Engineering, Yibin University, Yibin, China.

Genetics Department, Faculty of Agriculture, Zagazig University, Zagazig, Egypt.

出版信息

Front Plant Sci. 2021 Sep 7;12:705249. doi: 10.3389/fpls.2021.705249. eCollection 2021.

Gene silencing is a negative feedback mechanism that regulates gene expression to define cell fate and also regulates metabolism and gene expression throughout the life of an organism. In plants, gene silencing occurs transcriptional gene silencing (TGS) and post-transcriptional gene silencing (PTGS). TGS obscures transcription the methylation of 5' untranslated region (5'UTR), whereas PTGS causes the methylation of a coding region to result in transcript degradation. In this review, we summarized the history and molecular mechanisms of gene silencing and underlined its specific role in plant growth and crop production.