Ellis G L, Shmookler B M
Oral Surg Oral Med Oral Pathol. 1986 May;61(5):471-8. doi: 10.1016/0030-4220(86)90390-7.
Although the calcifying odontogenic cyst (COC) is a well-established pathologic entity, it has been recognized that there is an odontogenic neoplasm with histologic features similar to the COC that has often been diagnosed as COC. Investigators have applied several terms to this neoplasm, but we prefer the term epithelial odontogenic ghost cell tumor (EOGCT). No reports have appeared previously in the literature describing either carcinoma arising in a COC or malignant EOGCT. Three cases are reported here with aggressive growth and histologic features strongly implying a malignant potential, although none is known to have metastasized. Two occurred in the maxilla and one in the mandible. One was discovered 9 years following removal of a typical COC, and another recurred rapidly after excision.
尽管牙源性钙化囊肿（COC）是一种已明确的病理实体，但人们已经认识到存在一种具有与COC相似组织学特征的牙源性肿瘤，该肿瘤常被诊断为COC。研究人员对这种肿瘤使用了多个术语，但我们更倾向于使用上皮性牙源性幽灵细胞瘤（EOGCT）这一术语。此前文献中尚无关于COC发生的癌或恶性EOGCT的报道。本文报告了3例具有侵袭性生长且组织学特征强烈提示有恶性潜能的病例，尽管尚无已知发生转移的病例。2例发生在上颌骨，1例发生在下颌骨。1例在切除典型的COC后9年被发现，另1例在切除后迅速复发。
