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中国山西省五个县2010 - 2016年围孕期被动吸烟与子代神经管缺陷风险

Passive Smoking During the Periconceptional Period and Risk for Neural Tube Defects in Offspring - Five Counties, Shanxi Province, China, 2010-2016.

作者信息

Zhang Yali, Liu Jufen, Zhang Le, Jin Lei, Greene Nicholas D E, Li Zhiwen, Ren Aiguo

机构信息

Institute of Reproductive and Child Health/Key Laboratory of Reproductive Health, National Health Commission of the People's Republic of China, Peking University, Beijing, China.

Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.

出版信息

China CDC Wkly. 2021 Sep 10;3(37):778-782. doi: 10.46234/ccdcw2021.193.

Abstract

WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: Passive smoking during pregnancy, which is prevalent in China, has been reported to be associated with an increased risk for neural tube defects (NTDs) in five counties of Shanxi Province in northern China.

WHAT IS ADDED BY THIS REPORT?: After 4 years since the implementation of the World Health Organization (WHO) Framework Convention on Tobacco Control (FCTC) in China, 59.4% of mothers of NTDs cases and 29.4% of mothers of healthy controls reported passive smoking during the periconceptional period. The association between periconceptional passive smoking and an increased risk for NTDs remains in the study population.

WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: It's urgent to take measures to prevent passive smoking among pregnant women to minimize the harmful effects on offspring.

摘要

关于该主题已知的信息有哪些?:在中国,孕期被动吸烟现象普遍,据报道,中国北方山西省的五个县中,孕期被动吸烟与神经管缺陷(NTDs)风险增加有关。

本报告新增了哪些内容?:自世界卫生组织(WHO)《烟草控制框架公约》(FCTC)在中国实施4年后,59.4%的神经管缺陷病例母亲和29.4%的健康对照母亲报告在受孕前后期间有被动吸烟情况。在研究人群中,受孕前后被动吸烟与神经管缺陷风险增加之间的关联依然存在。

对公共卫生实践有哪些启示?:迫切需要采取措施防止孕妇被动吸烟,以尽量减少对后代的有害影响。

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