Dunér-Engström M, Larsson O, Lundberg J, Fredholm B B
Swed Dent J. 1986;10(3):93-6.
The effect of nicotine, placebo for nicotine or menthol-tasting chewing gums on salivation was studied in 25 healthy volunteers. The chewing of a commercial nicotine containing (2 mg) chewing gum (Nicorette) did not give a larger rate of salivation than did the chewing of a placebo chewing gum. For both types of chewing gums the rate of salivation was highest during the initial 5 min and it decreased thereafter. Menthol-tasting chewing gum gave a significantly higher amount of stimulated saliva. It is concluded that the addition of nicotine to a chewing gum does not provide an additional stimulus for salivation.
在25名健康志愿者中研究了尼古丁、尼古丁安慰剂或薄荷味口香糖对唾液分泌的影响。咀嚼含尼古丁（2毫克）的商业口香糖（尼可戒）时，唾液分泌速率并不比咀嚼安慰剂口香糖时更高。对于这两种口香糖，唾液分泌速率在最初5分钟内最高，之后下降。薄荷味口香糖产生的刺激唾液量显著更高。得出的结论是，在口香糖中添加尼古丁不会对唾液分泌提供额外刺激。
