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采用 UPLC-ELSD 指纹图谱结合化学计量学方法评价芭蕉芋根茎、假茎和叶的化学成分相似性。

Evaluation of chemical similarity among rhizome, pseudo stem and leaf of Musa basjoo by UPLC-ELSD fingerprint combined with chemo metrics methods.

机构信息

Department of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang City, Guizhou Province, PR China.

Department of Pharmacy, The first affiliated Hospital University of Guizhou of traditional Chinese Medicine, Guiyang City, Guizhou Province, PR China.

出版信息

Pak J Pharm Sci. 2021 May;34(3):1003-1010.

PMID:34602425
Abstract

Rhizoma Musa (the Rhizome of Musa basjoo Sied.et Zucc.) is used as a traditional medical herb of Miao nationality in Guizhou province, in China. It has the efficacy of clearing heat and detoxifying, quenching thirst, diuresis, etc. Modern pharmacological studies have shown that it has hypoglycemic, inhibition of α-glucosidase, and anti-inflammatory activity. However, when the rhizomes of Musa basjoo are dug up, the rhizomes are unable regenerate, and the pseudostem and leaf are discarded, which not only pollutes the environment, but also causes a huge waste of herb resources. In this study, a UPLC-ELSD fingerprint analysis with chemometric method was applied for the evaluation of chemical similarity among rhizome, pseudostem and leaf of Musa Basjoo. The results indicated that the combined method could efficiently analyze and compare the chemical similarity among rhizome, pseudostem, and leaf of Musa Basjoo. The proposed method provides the foundation for the resource substitution of the rhizome, pseudostem, and leaf of Musa Basjoo.

摘要

芭蕉芋(芭蕉科芭蕉属美人蕉组植物芭蕉芋)是中国贵州省苗族的一种传统药用植物,具有清热、解毒、解渴、利尿等功效。现代药理学研究表明,它具有降血糖、抑制α-葡萄糖苷酶和抗炎活性。然而,当芭蕉芋的根茎被挖出时,根茎无法再生,假茎和叶子被丢弃,这不仅污染环境,而且造成草药资源的巨大浪费。在这项研究中,应用了一种基于 UPLC-ELSD 的化学计量学指纹分析方法来评估芭蕉芋根茎、假茎和叶子之间的化学相似性。结果表明,该联合方法可以有效地分析和比较芭蕉芋根茎、假茎和叶子之间的化学相似性。该方法为芭蕉芋根茎、假茎和叶子的资源替代提供了基础。

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