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猫异位胸腺瘤相关剥脱性皮炎和寻常型天疱疮合并症。

Comorbidity of ectopic thymoma-associated exfoliative dermatitis and pemphigus foliaceus in a cat.

机构信息

Clinical Science, Section of Dermatology (Mendoza-Kuznetsova), Biomedical Sciences, Section of Pathology (Piedra-Mora), Tufts University Cummings School of Veterinary Medicine, North Grafton, Massachusetts 01536, USA; North Carolina State University College of Veterinary Medicine, 1060 William Moore Drive, Raleigh, North Carolina 27606, USA (Bizikova).

出版信息

Can Vet J. 2021 Oct;62(10):1067-1070.

PMID:34602633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8439328/
Abstract

An 8-year-old cat was presented with pruritus, purulent paronychia, scaling, crusting, and spontaneous alopecia. Histopathology revealed intraepidermal neutrophilic pustular acantholytic dermatitis and hyperkeratotic cytotoxic interface dermatitis. No thoracic mass was seen on a lateral radiograph. Ectopic thymoma was discovered on necropsy. This case highlights the necessity for thorough investigation of any case of feline exfoliative dermatitis and pemphigus foliaceus for the presence of thymoma. Key clinical message: Comorbidity of exfoliative dermatitis and pemphigus foliaceus in a cat should prompt a thorough investigation for presence of a thymoma, possibly with advanced imaging techniques.

摘要

一只 8 岁的猫出现瘙痒、脓性甲周炎、鳞屑、结痂和自发性脱毛。组织病理学显示表皮内中性粒细胞脓疱性棘层松解性皮炎和角化过度细胞毒性界面性皮炎。侧位 X 光片未见胸腔肿块。尸检发现异位胸腺瘤。本病例强调了在任何猫的表皮松解性皮炎和落叶性天疱疮病例中,都需要彻底调查胸腺瘤的存在。关键临床信息:猫的表皮松解性皮炎和落叶性天疱疮合并存在时,应彻底调查胸腺瘤的存在,可能需要使用先进的成像技术。

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本文引用的文献

1
Paraneoplastic pemphigus in a dog.犬副肿瘤性天疱疮
Vet Dermatol. 1998 Jun;9(2):127-134. doi: 10.1046/j.1365-3164.1998.00095.x.
2
Clinicopathological findings and clinical outcomes in 49 cases of feline pemphigus foliaceus examined in Northern California, USA (1987-2017).美国加利福尼亚州北部(1987 - 2017年)检查的49例猫落叶性天疱疮的临床病理结果及临床转归
Vet Dermatol. 2019 Jun;30(3):209-e65. doi: 10.1111/vde.12731. Epub 2019 Feb 18.
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Feline pemphigus foliaceus: original case series and a comprehensive literature review.猫落叶性天疱疮:原始病例系列及全面文献综述
BMC Vet Res. 2019 Jan 9;15(1):22. doi: 10.1186/s12917-018-1739-y.
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The spectrum of ectopic thymomas.异位胸腺瘤的谱系
Virchows Arch. 2016 Sep;469(3):245-54. doi: 10.1007/s00428-016-1967-0. Epub 2016 Jun 2.
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Putative paraneoplastic pemphigus and myasthenia gravis in a cat with a lymphocytic thymoma.一只患有淋巴细胞性胸腺瘤的猫出现疑似副肿瘤性天疱疮和重症肌无力。
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High prevalence of infections and autoimmunity in patients with thymoma.胸腺瘤患者感染和自身免疫的高发率。
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Diagnosis of erythema multiforme associated with thymoma in a dog and treated with thymectomy.犬胸腺瘤相关多形红斑的诊断及胸腺切除治疗
J Am Anim Hosp Assoc. 2011 Mar-Apr;47(2):e19-25. doi: 10.5326/JAAHA-MS-5561. Epub 2011 Feb 10.
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Cervical thymoma originating in ectopic thymic tissue in a cat.源自猫异位胸腺组织的颈部胸腺瘤。
Vet Clin Pathol. 2008 Dec;37(4):397-402. doi: 10.1111/j.1939-165X.2008.00061.x.
9
Metastatic thymoma and acquired generalized myasthenia gravis in a beagle.一只比格犬的转移性胸腺瘤与获得性全身性重症肌无力
Can Vet J. 2007 Jan;48(1):91-3.
10
Thymoma-associated exfoliative dermatitis in cats.猫胸腺oma相关剥脱性皮炎
Vet Pathol. 2004 Jul;41(4):429-33. doi: 10.1354/vp.41-4-429.