Kapatia Gargi, Wadhwa Monika, Malhotra Pankaj, Prakash Gaurav, Aggarwal Ritu
Department of Immunopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
J Lab Physicians. 2021 Sep;13(3):219-223. doi: 10.1055/s-0041-1730878. Epub 2021 Jun 16.
The incidence of a bifid electrophoretic pattern in the albumin region on serum protein electrophoresis is an infrequent phenomenon. The availability of literature from India is scarce and is limited to case reports. The aim of the study is to analyze the frequency of bisalbuminemia in an Indian referral facility. The study delved into their clinical associations. The retrospective case records of the patient from the departmental database were scrutinized. The study subjects were for an 8-year study period. There were about 39,900 serum electrophoresis performed in an 8-year study period. A total of 40 cases of bisalbuminemia were detected. The incidence in our cohort was 0.01%. Bisalbuminemia, an overtly benign condition, is infrequent in Indian population although not rare. It is associated with several clinical disorders; however, the association seems to be plausibly coincidental.
血清蛋白电泳中白蛋白区域出现双峰电泳图谱的情况是一种罕见现象。来自印度的相关文献资料匮乏，且仅限于病例报告。本研究的目的是分析一家印度转诊机构中双白蛋白血症的发生率，并深入研究其临床关联。我们仔细查阅了部门数据库中患者的回顾性病例记录。研究对象为8年研究期内的患者。在8年的研究期内共进行了约39900次血清电泳，共检测出40例双白蛋白血症病例。我们队列中的发生率为0.01%。双白蛋白血症是一种明显良性的病症，在印度人群中虽不罕见但也较为少见。它与多种临床疾病相关；然而，这种关联似乎很可能只是巧合。
