Department of Emergency, Hong Hui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi 710054, China.
Department of Emergency Intensive Care Unit, Lanzhou University of Second Hospital, Lanzhou, Gansu 730030, China.
Chin Med J (Engl). 2021 Oct 4;134(22):2647-2655. doi: 10.1097/CM9.0000000000001772.
Cell death occurs in various tissues and organs in the body. It is a physiological or pathological process that has different effects. It is of great significance in maintaining the morphological function of cells and clearing abnormal cells. Pyroptosis, apoptosis, and necrosis are all modes of cell death that have been studied extensively by many experts and scholars, including studies on their effects on the liver, kidney, the heart, other organs, and even the whole body. The heart, as the most important organ of the body, should be a particular focus. This review summarizes the mechanisms underlying the various cell death modes and the relationship between the various mechanisms and heart diseases. The current research status for heart therapy is discussed from the perspective of pathogenesis.
细胞死亡发生在体内的各种组织和器官中。它是一种具有不同影响的生理或病理过程。它对于维持细胞的形态功能和清除异常细胞具有重要意义。细胞焦亡、细胞凋亡和细胞坏死都是细胞死亡的方式，已经被许多专家学者广泛研究，包括它们对肝脏、肾脏、心脏等器官，甚至全身的影响的研究。心脏作为人体最重要的器官，应该是一个特别关注的焦点。本文综述了各种细胞死亡方式的机制以及各种机制与心脏病之间的关系。从发病机制的角度讨论了目前心脏治疗的研究现状。
