Lee Yerim, Ng Michelle, Daniel Kristin, Wayne Elizabeth
Department of Biomedical Engineering, and Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, PA USA.
MRS Bull. 2021;46(9):847-853. doi: 10.1557/s43577-021-00185-2. Epub 2021 Sep 29.
From Operation Warp Speed to the lipid mRNA vaccine, the COVID-19 pandemic has been a watershed moment for technological development, production, and implementation. The scale and pace of innovation and global collaboration has likely not been experienced since World War II. This article highlights some of the engineering accomplishments that occurred during the pandemic. We provide a broad overview of the technological achievements in vaccine design, antibody engineering, drug repurposing, and rapid diagnostic testing. We also discuss what the future of these technologies and the future of large-scale collaborations might look like moving forward.
从“曲速行动”到脂质信使核糖核酸疫苗,新冠疫情成为了技术发展、生产和应用的一个分水岭时刻。自第二次世界大战以来,创新和全球合作的规模与速度可能从未有过。本文重点介绍了疫情期间取得的一些工程成就。我们对疫苗设计、抗体工程、药物再利用和快速诊断测试方面的技术成果进行了广泛概述。我们还讨论了这些技术的未来以及大规模合作的未来发展方向。